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CSK Research Solutions, Mtwara, Tanzania Salum Mshamu Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK Salum Mshamu London School of Hygiene and Tropical Medicine, London, UK John Bradley The Royal Danish Academy–Architecture, Design, Conservation, Copenhagen, Denmark Thomas...
Abnormal alterations in human epidermal growth factor receptor 2 (HER2, neu, and erbB2) are associated with the development of many tumors. It is currently a crucial treatment for multiple cancers. Advanced in molecular biology and further exploration of
Cells were then processed for immunofluorescence to detect the localization of LYP and SLP76. Microclusters began to form in these assays after 3 min of stimulation and were present in all cells after 5 min (data not shown). We found that LYP colocalized with SLP76 in microclusters (Fig. ...
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form a quaternary complex. In the presence of SUSD6 and TMEM127, WWP2 mediates MHC-I ubiquitination as well as lysosomal degradation, thereby reducing MHC-I surface expression, loss of SUSD6 enhances MHC-I surface expression, which can promote the function of CD8+T cells, thereby enhancing ...
Myocarditis is an inflammation of the heart muscle most often caused by viral infections. Sex differences in the immune response during myocarditis have been well described but upstream mechanisms in the heart that might influence sex differences in disease are not completely understood. Methods Male ...
Although the intact form of CD6 is the most abundant in T cells, an isoform lacking d3 (CD6∆d3) is transiently expressed on activated T cells. Still, the precise character of the signaling transduced by CD6, whether costimulatory or inhibitory, and the influence of its ectodomain on ...
The amount of the gathered data prompted us to present them in the form of a searchable catalog – the YaliFunTome database (https://sparrow.up.poznan.pl/tsdatabase/)—to facilitate the withdrawal of biological sense from numerical data. We succeeded in the identification of TFs that act ...
During the IPL 2024 auction in Dubai, Gujarat Titans made notable investments in uncapped players, highlighting their strategic focus on emerging talent. Their most substantial acquisition came in the form of Brisbane Heat's left-arm fast bowler Spencer Johnson, secured for a staggering Rs 10 crore...