However, excess copper can disrupt cellular homeostasis, leading to the induction of cuproptosis. This form of cell death is characterized by the aggregation of lipoylated proteins in the tricarboxylic acid (TCA) cycle, resulting in proteotoxic stress and ultimately triggering mitochondrial dysfunction ...
Comparison of research indicators among the brace monitoring rehabilitation group (BMRG), telephone-guided rehabilitation group (TGRG), and conventional rehabilitation group (CRG). (a) Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores. (b) Hospital for Special Surgery (HSS)...
Cuproptosis, a form of regulated cell death (RCD), is characterized by the direct binding of copper to fatty acylated components of the mitochondrial respiratory tricarboxylic acid (TCA) cycle, inducing protein toxic stress that ultimately leads to cell death. Key cancer-related processes such as ...
Patients included were those who had any form of an AR (i.e., high or low) or a RH operation performed between January 2009 and December 2019 at Concord Repatriation General Hospital (CRGH), Sydney. These patients were identified from a prospectively maintained institutional database that has...
Multi-display interface: Standard, Large font, Trend Coexist, OxyCRG dynamic, 7 full ECG waveforms; Language: Built-in 8 language for choose (English, Chinese, Turkish, Spanish, French, Russian, German, Italia...
In the recent years, cuproptosis, a novel form of regulated cell death which is copper dependent has been identified [1,2], may be implicated in the process of various cancers. Copper is a trace element in the human body and has been strongly associated with various signaling pathways and ...
The primary form of treatment for TNBC patients is conventional cytotoxic systemic chemotherapy. Primarily, they are susceptible to conventional chemotherapy but the initial susceptibility to this treatment does not correlate with overall survival in TNBC patients who have acquired complete remission. Among...
Lower numbers for authenticity in texts, found in PLSs, may be associated with a more guarded, distanced form of discourse [24]. Comparing the categories of conclusiveness, we found that authenticity was slightly higher in vague, inconclusive summaries. As higher authenticity suggests honest, ...
CNAG-CRG, Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain Holger Heyn Contributions IH, WE, and PJ conceptualized this study. IH and PJ wrote the original draft. PJ, BV, and ZK conducted the formal analysis. SS did the data curation. XA, JM,...
The authors would like to thank the Genomics Unit at the CRG for assistance with the miRNAseq analysis. Funding This work was supported in part by grants from the Instituto de Salud Carlos III PI19/00245, PI22/00230, and the RETICS Program (RD16/0011/0004), co-funded by FEDER “una ...