Yong CQY, Valiyaveettil S, Tang BL. Toxicity of Microplastics and nanoplastics in mammalian systems. Int J Environ Res Public Health 2020, 17(5). Deng Y, Zhang Y, Lemos B, Ren H. Tissue accumulation of microplastics in mice and biomarker responses suggest widespread health risks of exposure...
Polarized light microscope (Carl Zeiss Axio Scope A1, Germany) was used to identify the species of the wooden stick (SHZ4), straws (SHZ3) and the raw material used in making the paper costumes (CQY5 and FXL4) and decorations (CQY2 and CQY3), as well as determine the deep blue pigm...
form, that is based on (or derived from) the Work and for which the editorial revisions, annotations, elaborations, or other modifications represent, as a whole, an original work of authorship. For the purposes of this License, Derivative Works shall not include works that remain separable from...
represented by a single chain of the variable region of a monoclonal antibody, with an ζ-chain of the intracellular TCR deputed to signal transduction, joined by an intermediate (hinge) region and a transmembrane region. Although first-generation CAR-Ts have been effective...
of the human prion protein exhibit a number of hydrophobic cavities in the well-folded core (amino acids 125 to 231) but the full length prion protein may also transiently form new cavities when the presumably disordered N-terminus gets in contact with the compactly folded part of the protein...
Innovative Medicine worldwide operational sales, excluding the COVID-19 Vaccine, grew 7.2%*. Growth was driven by DARZALEX (daratumumab), ERLEADA (apalutamide), TECVAYLI (teclistamab-cqyv) in Other Oncology, and CARVYKTI (ciltacabtagene autoleucel) in Oncology, STELARA (ustekinumab) and TREMF...
A further list and descriptions of these risks, uncertainties and other factors can be found in Johnson & Johnson’s Annual Report on Form 10-K for the fiscal year ended January 2, 2022, including in the sections captioned “Cautionary Note Regarding Forward-Looking Statements” and...
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The latter impairment is the most serious form of DNA damage [135]. A disfigured genome is the stimulus that initiates DNA damage response (DDR) processes [136,137]. These consist of a series of complex events that heal the DNA lesions. When the damage is highly deleterious, however, it ...
Also the hydrodynamic diameter of particles, or secondary particle size, may be of importance with respect to particle neurotoxicity. While smaller particles may seem more neurotoxic, they are also more likely to cluster together and form aggregates. While aggregation increases (secondary) particle siz...