This promotes angiogenesis and exacerbates hypoxia; (iii) Moreover, CAFs increase tissue fluid pressure and form a dense barrier within the tumor tissue. Consequently, nanocarriers are unable to penetrate deeper into the tumor sites, leading to a decrease in the EPR effect [114,115,116,117,118...
Digital twin (DT) technology is also known as digital avatars [1], digital masters [2], digital shadows [3], etc. It is a technology that accomplishes the mapping of the real world to the digital world and realizes the interaction between them in real time. This technology overcomes the ...
The subjects will be randomly allocated, and the investigational drugs will be allocated in the Central Randomization System of Clinical Information Management System (CIMS-CRS). After signing the informed consent form, each subject will be given a screening number. The length of the screening ...
The analogical information of the source system, including source design problems and solution, was mined comprehensively through International Patent Classification analysis and represented in the form of function, behavior and structure. Three heuristics were suggested for searching the set of candidate ...
The presence of a decision to withhold/withdraw a life-sustaining measure at any time during the ICU stay was also recorded. On the case report form, investigators recorded urine output in milliliters as a total for each 24-h period. On the day of admission, urine output data were ...
(DAS), Short Form 36 (SF-36), Child Health Questionnaire (CHQ), physician global damage, Myositis Damage Index (MDI), Quantitative Muscle Testing (QMT), Myositis Functional Index-2 (FI-2), Myositis Activities Profile (MAP), Inclusion Body Myositis Functional Rating Scale (IBMFRS), Cutaneous...
We understand trust 'in rational or calculative terms, as a form of confidence based on incentives, rules, or institutional features that gives one person reason to believe that another person will protect his or her interests' [[1]: 1133]. Most analyses of trust in the health sphere focus...
Protons are simultaneously generated in the anode chamber, passively transferred to the cathode chamber through a membrane and react with oxygen molecules on the cathode electrode to form water molecules. All these steps influence the total efficiency (e.g., power density, coulombic efficiency and ...
A set of random variables (nodes) and a set of oriented arcs connecting the random variables which form a Direct Acyclic Graph (DAG). A finite set of mutually exclusive states associated with each random variable. For each random variable X with parents Y 1,…,Y n a CPT encoding the ...
OP06 The influence of multivalency on CCK 2 receptor targeting D. Summer, A. Kroess, C. Rangger, H. Haas, P. Laverman, F. Gerben, E. von Guggenberg, C.Decristoforo OP07 SPECT Imaging of αvβ3 Expression by [99mTc(N)PNP43]- Bifunctional Chimeric RGD Peptide not Cross-Reacting with...