found that VEGFR2 antibody fused with a mutated form of IFN-α could effectively modulate the TME of CRC, producing anti-tumor and anti-metastatic effects [6]. Wei et al. demonstrated that enhanced ketogenesis could ameliorate the immunosuppressive TME by suppressing KLF5-dependent CXCL12 expression...
Ciampor, Fedor(f.ciampor@savba.sk)Coleoptera: DRYOPOIDEA ZooLab, Institute of Botany, Slovak Academy of Sciences, Dúbravská cesta 9, 84502 Bratislava, SLOVAKIA Clarke, Dave J.(djclarke@memphis.edu)Coleoptera: CURCULIONOIDEA(Weevils) Department of Biological Sciences, The University of Memphis...
These exosome-liposome hybrids have been shown to form structures larger than 200 nm [113], and ultrafiltration can separate them from smaller mixtures of exosomes and liposomes. Researchers have successfully synthesized folate-modified exosome-liposome hybrid nanoparticles loaded with ALKBH5 mRNA, which...
Therefore, breeders and germplasm banks play a fundamental role in contributing to the stability of agricultural incomes and ensuring the competitiveness of farms. Ryegrass seeds conserved in the Germplasm Bank of the Agricultural Research Centre of Mabegondo (CIAM), have been continually requested by ...
Large-scale phenotype data can enhance the power of genomic prediction in plant and animal breeding, as well as human genetics. However, the statistical foundation of multi-trait genomic prediction is based on the multivariate linear mixed effect model,
(Ha et al.2021). In many cases, disinformation can be a form of propaganda. By creating and spreading false narratives, actors can manipulate public perception and behavior to align with their goals. For instance, a political actor might disseminate disinformation about an opponent’s policies ...
DA can be regarded as a data driven form of farming, in which decision-making processes are based on explicit information derived from data collected through various sources [148]. DA and Precision Agriculture (PA) seem to refer to the same thing, however, as stated in [148], DA involves...
Insulin resistance (IR) is defined as a key pathophysiological feature in PCOS, contributing to hyperandrogenism and worsening the clinical presentation of PCOS. While lean women present with IR in a form that is mechanistically different from IR caused by excess weight, overweight and obesity furth...
Fontana L, Adelaiye RM, Rastelli AL, Miles KM, Ciamporcero E, Longo VD, Nguyen H, Vessella R, Pili R. Dietary protein restriction inhibits tumor growth in human xenograft models of prostate and breast cancer. Oncotarget. 2013;4(12):2451–61. Article PubMed PubMed Central Google Scholar...
Global, detailed and comprehensive reconstructions of human metabolism and signalling pathways exist in the form of molecular maps, but they have never been integrated together. We aim at filling in this gap by integrating of both signalling and metabolic pathways allowing a visual exploration of ...