Methods: PRP19 expression was augmented in cultured A549 cells via plasmid transfection. Growing cells were subjected to various cell survival and apoptosis assays including CCK-8, DAPI, TUNEL and FITC-Annexin V staining. Lysates were obtained from harvested cells for immuno...
Research on chickens (Gallus gallus) has had a significant impact on fundamental biology. The domestic chicken also provides a major protein source from meat and eggs for most human populations throughout the world. Its economic importance has made it the focus of numerous research projects, ...
Jin-Gui-Shen-Qi Wan (JGSQ) has been used in China for thousands of years to treat various ailments, including frequent urination, blurred vision, and soreness in the waist and knees. It has traditional therapeutic advantages in improving eye diseases. Cl
Conclusions Altogether, our findings highlight the functional role of MELK as a promising target in molecular therapy and in the combination of RT therapy to improve antitumor effect for HCC.Background Hepatocellular carcinoma (HCC), the most prevalent form of primary liver cancer, ranked as the ...
Aromatase catalyzes the synthesis of estrogens from androgens. Knowledge on its regional expression in the brain is of relevance to the behavioral implications of these hormones that might be linked to sex differences in mental health. The present study
Subsequently, cluster analysis was conducted on the differentially expressed genes, which was displayed in the form of a heatmap (Fig. 2F-2H). It can be seen from the above results that replacing FBS with PRP in culture system can improve the gene expression ability of cells. At the same ...
of small intestinal crypts and are long-lived, whereas other mature lineages move up to keep the crypt or villus structures. These cell types cooperate with each other to form a multifunctional network. After the functional performance, these mature cells undergo cell death in a cycle of 4–5...
Armadillo Repeat Containing X-Linked 1 (ARMCX1), a member of the ARM Repeat X-linked protein family, exerts inhibitory function in various tumors. However, its biological role in lung adenocarcinoma (LUAD) and the underlying molecular mechanisms require
This study investigated the mechanism of the extracellular matrix-mimicking hydrogel-mediated TGFB1/Nrf2 signaling pathway in osteoarthritis using bone marrow mesenchymal stem cell-derived exosomes (BMSCs-Exos). A GMOCS-Exos hydrogel was synthesized and
Extracellular vesicles (EVs) play an important role in human and bovine milk composition. According to excellent published studies, it also exerts various functions in the gut, bone, or immune system. However, the effects of milk-derived EVs on skeletal