boiling point solvent that can dissolve the selected metal ions and organic ligands at a specific temperature, providing a stable environment for the synthesis reaction; (3) Mixing the selected metal ions and organic ligands in a certain proportion in the chosen solvent to form a precursor mixture...
CD47 can be found in a bigger, more complex form associated with heparin and chondroitin sulfate glycosaminoglycan. This form is expressed in both human and murine T-cells as well as endothelial cells and is responsible for signal inhibition after binding of T-cells to thrombospondins (TSPs) [...
CircRNAs further possess multiple miRNA response elements of different miRNAs, such as circHIPK3 [27], while there is also evidence to suggest that multiple circRNAs can regulate the same miRNA simultaneously. Subsequently, the miRNAs initially targeted mRNA will bind with circRNAs, and form a circ...
Similarly, evidence has shown that primary cancers can induce secondary organs to gradually form a supportive microenvironment called the pre-metastatic niche [5]. Therefore, the TME is one of the key factors that affect cancer metastasis and growth. As the importance of the TME to cancer ...
Rice and maize pollen grains begin to accumulate starch at stage 11 and form numerous large starch granules by maturity (Chang et al. 2016; Zhang et al. 2018a). The PG47 promoter driving the ZmAA1 gene can effectively prevent the formation of starch granules in pollen grains carrying the ...
Secondary malignant bone tumors originate from other organs or tissues and metastasize to the bone. The most prevalent form of secondary malignant bone tumor is bone metastasis (BM) [3]. Apart from metastatic bone tumors, secondary malignant bone tumors also include leukemic infiltration of bone, ...
of cancer cells, and cisplatin exerts its cytotoxic effect by inducing DNA damage and disrupting the protective DDR mechanisms [27]. γH2AX, the phosphorylated form of histone H2AX at Ser139, marks an early cellular response to DNA double-strand breaks (DSBs), initiating and activating the DDR...
Multiple myeloma (MM) is a form of hematological malignancy, which originates in the bone marrow (BM), accounting for 10% of hematological malignancies and 1% of the total cancer occurrence worldwide [1]. The annual incidence rate of MM in Europe alone is expected to be 4–6 cases/100,...
The p50 and p52 proteins are generated by proteolytic processing of their precursors, p105 and p100, respectively. With the exception of RelB, all members of the NF-κB family have the ability to form homodimers as well as heterodimers. The most common activated form of NF-κB consists of ...
The adjacency matrix of Wm in graph Gm is a symmetric matrix. In this paper, “Heat Kernel” is used to measure the similarity between samples [18]. The basic form is a Gaussian function with “t”. It has linear complexity and robustness that is not sensitive to small changes. Sijm=...