Immune checkpoint inhibitors (ICIs) have emerged as a novel and effective treatment strategy, yet their effectiveness is limited to a subset of patients. The gut microbiota, recognized as a promising anticancer adjuvant, is being increasingly suggested t
Taxol serves as an efficient natural anticancer agent with extensive applications in the treatment of diverse malignancies. Although advances in synthetic biology have enabled the de novo synthesis of taxol precursors in various microbial chassis, the to
Notably, circulating levels of FFAs, including palmitate, are greatly elevated in T2D, and can drive EC dysfunction [15, 19]. Recently, lipid droplets were shown to dynamically form and disassemble in ECs following exposure to FFAs [40]. We transfected HUVEC with control or miR-30e mimic and...
Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012;149(5):1060–72. Article PubMed PubMed Central CAS Google Scholar Feng X, Wang S, Sun Z, et al. Ferroptosis enhanced diabetic renal tubular injury via HIF-1α/HO-1 pathway in db/db mice. Front Endocrinol. ...
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Short Form of the Brief Pain Inventory FACT-G: Functional Assessment of Cancer Therapy – General (any tumor type) FACT-P: Functional assessment of cancer therapy for prostate cancer FAPSI: FACT Advanced Prostate Symptom Index HRQoL: Health-Related Quality of Life MCID: Minimal clinically...
(CFH-related proteins 4) is a complement in the form of CFH cofactor-enhancing activity that modulates activity. It binds to the central complement component C3b [105,106]. Besides, the expression of CLU was decreased in total exosomes and increased in placenta-derived exosomes. Clusterin ...
According to the subread data, each Read of Insert (ROI) was identified, and then the consensus form of each ROI was integrated. The full-length non-chimeric reads and the non-full-length reads of the ROIs were used for the next analysis. The full-length non-chimeric reads were gathered...
Fluid normally exchanges freely between the plasma and interstitial space and is returned primarily via the lymphatic system. This balance can be disturbed by diseases and medications. In inflammatory disease states, such as sepsis, the return flow of fl
or in the form of polylactosamine units (glycan no. 542, 545, 546, 548, 578, 585, 604, 608 etc.). Bioinformatics analysis indicated that ATL is synthesised as a secretory protein with a N-terminal signal peptide. Mature ATL polypeptide undergoes another C-terminal cleavage and has two ...