Ascites is the form of late peritoneal fluid, contains a substantial number of tumor and immune cells that can interact with each other, generating and responding to mediators with properties that promote metastasis and suppress the immune system. LPAR1, LPAR2 and LPAR3 are expressed mainly in ...
The CreERT2 fusion protein consists of Cre recombinase fused to a triple mutant form of the human estrogen receptor, which does not bind its natural ligand (17β-estradiol) at physiological concentrations but will bind the synthetic estrogen receptor ligand 4-hydroxytamoxifen. All mice were housed...
Library preparation and sequencing workflow for both PacBio and ONT. PacBio workflow: DNA is first extracted from blood or cell lines and then sheared to the desired fragment size (typically at 15–25 kbp). After DNA end repair, fragments are ligated to adapters to form circular molecules cal...
Recently, a growing body of research has indicated that chitinase-3-like protein 1 (CHI3L1; also known as breast regression protein 39 [BRP-39] in mice) may serve as an important marker of chronic inflammation and subsequently promote tumor progression [7,8,9,10]. First, it exacerbates oxid...
, but they appear to be separated by a cleft in paraffin sections due to tissue shrinkage during processing. In histological sections, this apparent scissure has a characteristic sigmoidal shape at e14.5 (Fig.1A). The dorsal side of the cleft, adjacent to the posterior lobe, will form the ...
For the three protein forms the ATG resides in exon 2 (RA, RC, RD), and for the fourth form resides in exon 3 (RB). To inactivate the gene completely, we decided to delete a region of 1507 bp starting 9 bp upstream of the ATG in exon 2, including the intron between exons ...
of UNCLOS disputes concerning, among others, maritime delimitation, historic bays or titles, military and law enforcement activities. Such declarations made by about 30 states, including China, form an integral part of the UNCLOS dispute settlement mechanism. By camouflaging its submissions, the ...
94. Still worse, on 9 May 1999, the Philippines sent BRP Sierra Madre (LT-57), a military vessel, to intrude into China’s Ren’ai Jiao and illegally ran it aground on the pretext of “technical difficulties”. China immediately made solemn representations to the Philippines, demanding the...
coli expression has the potential to produce high yields of a protein, it can be found in an insoluble form in inclusion bodies. There are a number of ways in which this problem can be avoided, for example (1) careful choice of growth conditions can reduce the rate of protein production ...
Hi, I was directed here from the draw.io feedback form. What is your preferred solution, to remove the warning and show all the text without line breaks? That would be my preferred solution, or even better to have this a user-editable option. I'm also seeing my text getting replaced ...