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Integrins, comprised of α and β subunits non-covalently bound together, form heterodimeric complexes found in endothelial cells, pericytes, fibroblasts, and tumor cells. In mammals, there are a total of 18 α subunits and 8 β subunits. Through their mutual combinations, at least 24 αβ inte...
The reduction in system latency provides faster response and a more power efficient system that can reduce the large carbon footprint of data centers. Additional information is available at https://www.brainchipinc.com Contact BrainChip Fill out this form for contacting a BrainChip representative. ...
Then, neurons can migrate in two different ways: radial and tangential migration; the first one represents the principal form of migration in the cerebrum, in which neurons move perpendicularly to the ventricular surface since the proper layer; the second is mainly used by inhibitory interneurons ...
The fully glycosylated MUC1-N subunit extends above the glycocalyx to form a physical barrier that can produce a lubricating effect on mucosal surfaces and protects cells from external physicochemical factors (infections, toxins, physical damage, and other forms of stress) [30,31,32]. MUC1-C ...
Single nucleotide polymorphism (SNP), a common form of genetic variation, is caused by the transition, transversion, insertion, or deletion of individual bases. Expression quantitative trait loci (eQTL) analysis can profile genetic variations (especially SNP) that affect gene expression, offering enhan...
We exposed retinal explants to Treg secretome in the presence or absence of a pro-inflammatory stimulus in the form of lipopolysaccharide (LPS) and investigated cone survival by staining for CA. LPS is a widely used pro-inflammatory activator of microglia and macrophages [33], which at least ...
Along a grassy strip separating the fairground parking lot from the beach, a cottage industry of disaster had sprung up in the form of several tents stocked with Thomas Fire–themed merchandise. Upon being confronted with a pink tee-shirt bearing the likeness of Santa and his reindeer flying ...
NEPC is rarely diagnosed de novo in its pure form (small cell or large cell prostate cancer, < 2% of first diagnoses) [10], but about 10-17% of patients with metastatic CRPC have been reported to progress with t-NEPC when treated with NHA [11]. Increased therapeutic pressure on the...
Intellectual disability (ID) can be caused by non-genetic and genetic factors, the latter being responsible for more than 1700 ID-related disorders. The broad ID phenotypic and genetic heterogeneity, as well as the difficulty in the establishment of the