Peripheral T-cell lymphoma (PTCL) is a rare and heterogeneous group of hematological malignancies. Compared to our knowledge of B-cell tumors, our understanding of T-cell leukemia and lymphoma remains less adva
Alzheimer’s disease (AD) is the most common form of dementia. It is characterized by the accumulation of amyloid-beta in senile plaques and hyperphosphorylated Tau in neurofibrillary tangles (NFTs) [22]. Mutations in the amyloid precursor protein (APP) or the proteins that cleave it, the pre...
At this point, workflow systems like for example Galaxy [14] or Conveyor [15] pose an interesting alternative to custom programming: Mainly specific to a certain application domain, they provide data processing capabilities in the form of small tasks; more complex analysis workflows are then devise...
The popular neighbor-joining (NJ) algorithm used in phylogenetics is a greedy algorithm for finding the balanced minimum evolution (BME) tree associated to a dissimilarity map. From this point of view, NJ is "optimal" when the algorithm outputs the tree
and some researchers have found that genes work together to form biological networks, which can be used to identify driver genes. MEMO [36] relies on the predictive pathway or the mutual exclusion of driving mutations in the sub-net to try to find a small sub-net of genes belonging to the...
The most popular shapes are those of whatever animal is the patron protector of that particular Chinese year-the rabbit, the tiger, the rat, the monkey, the horse, etc. Older children may take sticks of bamboo and stuff the hollow center with paper and oil-soaked rags to form a torch ...
Due to progressive retinal capillary dropout, the ischemic retina mounts an angiogenic response leading to a more advanced form of the disease, proliferative diabetic retinopathy [1]. However, the mechanism behind was not clear. HMGB-1 protein is a nuclear DNA binding protein released passively ...
The βPR region is a reflection of the βP region where a sequence of glycine residues in the βPR conformation will form a right-handed helix. Finally, there is a region that corresponds to the βS region of the generic Ramachandran plot. This region corresponds to the extended ...
storage in option 1 and for the model storage in option 2, we can assume that the storage cost of two options are the same (usually it is not the case because the model size is often smaller than the raw data because model can be considered as a form of abstraction of the raw data...
Such a result illustrates Mebkhout's and Narvaez's theorem which states that coherence and finite index conditions are equivalent. We also investigate on such isocrystals and elementary ^ (R) Q-modules what could be ...