A pentavalent involving five chromosomes will form during meiosis of male black muntjacs, whereas such structures are absent in female black muntjac. (b) Inversion on the neo-Y chromosome revealed by fluorescence in situ hybridization using two Indian muntjac bacterial artificial chromosome (BAC) ...
3c). Taking the negatively charged wall of the microchannel as an example, when the liquid contacts the negatively charged wall of the microchannel, the cations in the liquid gather on the wall of the microchannel to form a thin electric double layer (EDL) (0.1 nm-10 nm). Under the ...
Besides, we also utilize the binary classification metrics to evaluate the performance for each therapeutic peptide function prediction task in a one-versus-all form, including the area under the ROC curve (AUC) [17], Matthews’s correlation coefficient (MCC) [18], the F1 measure [19], and...
Jin-Gui-Shen-Qi Wan (JGSQ) has been used in China for thousands of years to treat various ailments, including frequent urination, blurred vision, and soreness in the waist and knees. It has traditional therapeutic advantages in improving eye diseases. Cl
In blood and urine, [68Ga]Ga-PSMA-Tz existed mainly in the form of the parent compound at 60 min p.i. (Additional file 1: Figure S13). The excellent stability both in vitro and in vivo provided prerequisites to realize the click-mediated pre-targeted in vivo. [68Ga]Ga-PSMA-Tz ...
2g). Similarly, full-length coverage with Smart-seq3xpress resulted in significantly (2–5-fold) increased read support over exon–exon and exon–intron splice junctions, which form the basis for RNA velocity inference16 (Fig. 2h). To perform a direct comparison of cluster granularity, we ...
Splenocytes were suspended in RPMI 1640 medium supplemented with 100 U/ml IL-2 and 10 μg/ml spike peptide pool, cultured in a 37 °C humidified incubator with 5% CO2 for 7 days. Subsequently, the splenocytes were washed and resuspended in a medium to be used as effector. ...
Then the primary bile acids are conjugated to form conjugated bile acid, followed by metabolism into secondary bile acids. Primary bile acids can be metabolized into secondary bile acids (DCA and LCA) by secondary BA-producing gut microbiota [65, 66]. DCA and LCA are potent endogenous ligands...
AGD1/USP10/METTL13 complexes diminished the sensitivity of docetaxel chemotherapy in CRPC through a mechanistic pathway. A-B. RNA pull-down assay combined with MS and western blot assays indicated that AGD1 associates with USP10 and METTL13 to form complexes. C. Co-IP assay demonstrated the...
The moisture diffusion coefficient (D), reflecting the rate of water transfer, can be determined from Fick’s second law in the form of a trigonometric series as following21,22: $$\frac{{{\rm{M}}}_{t}}{{M}_{e}}=\frac{2}{d}\sqrt{\frac{{Dt}}{\pi }}\,(0\ < \ \frac{{{...