Duchenne muscular dystrophy (DMD) is a severe form of muscular dystrophy without an effective treatment, caused by mutations in the DMD gene, leading to the absence of dystrophin. DMD results in muscle weakness, loss of ambulation, and death at an early age. Metabolomics studies in mdx mice,...
Advancement in technology, proper regulatory policies [17], tax deduction, and attempts in efficiency enhancement due to research and development (R&D) [18] are some of the pathways to conservation of energy and environment that should guarantee that renewable resource bases are used in a cost-eff...
This investigation revealed that lysine production is primarily controlled by aspartokinase (Ask) and lysine permease. This was verified by the experiment using the recombinant strain overexpressing Ask, resulting in the significant increase in lysine production, although that flux did not increase as ...
Considering that PINK1 has been identified as a target of PTEN, we investigated whether PINK1 could regulate PTEN to form a regulatory loop. In this study, we utilized a series of assays and identified the PINK1-PTEN interaction. Additionally, the phosphatidylinositol (PtdIns) (4,5)P2-binding d...
Many members of the oxysterol-binding protein-related protein (ORP) family have been characterized in detail over the past decades, but the lipid transport and other functions of ORP7 still remain elusive. What is known about ORP7 points toward an endopl
This investigation revealed that lysine production is primarily controlled by aspartokinase (Ask) and lysine permease. This was verified by the experiment using the recombinant strain overexpressing Ask, resulting in the significant increase in lysine production, although that flux did not increase as ...
jsHPAanalyze is a JavaScript software suite with a GPL-3 license designed to create an interface in which non-programmers can simulate the R software package environment. The different HPA data formats The HPA project provides data via two main mechanisms: Full datasets in the form of download...
[63,64]. Extended -10 promoters specifically interact with the conserved sigma factor region 3.0 to form the polymerase-promoter complex and often lack the -35 consensus element [65]. While it is assumed that the additional contact with the sigma factor in extended -10 promoters compensates ...
First, self-insufficiency of beef is directly affected by urbanisation and consumption behaviour and indirectly affected by urbanisation through the change of consumption behaviour; second, the change in consumption behaviour itself is contributed by rapid urbanisation; third, longer food miles of beef ar...
Smad5 (small mothers against decapentaplegic 5) protein is a receptor-regulated member of the Smad family proteins, mainly participating in the bone morphogenetic protein (BMP) signaling pathway in its phosphorylated form. This article will provide a det