As a neurodegenerative disease characterized by progressive loss of memory and cognitive impairment, Alzheimer’s disease (AD) is the most common form of dementia in the elderly [1, 2]. There are two pathological hallmarks of AD: extracellular deposits of amyloid-β (Aβ) protein and intracellul...
Moreover, it is reasonable to assume that different people prefer and require different levels of preventive activities. Some may be helped with working through a self-help manual, others could benefit from a minimal-contact psychotherapy, and still others may require a form of pharmacotherapy or ...
The ability of human recombinant 10xHis-XaSITE-α-globin-HA to interact in vitro with the previously produced 10xHis-XaSITE-TAT-β-globin-HA and form α-/β-globin heterodimers, was assessed and confirmed by size exclusion chromatography. The recombinant 10xHis-XaSITE-TAT-α-globin-HA was ...
12-Item short form health survey (SF-12) The health-related quality of life (HRQoL) will be measured with the SF-12. The SF-12 consists of 12 items on eight scales (‘physical functioning’, ‘role limitations due to physical problems’, ‘bodily pain’, ‘general health’, ‘vitality’...
where \overset{\sim }{u},\overset{\sim }{g},\overset{\sim }{t} are the Fourier transforms of u , g , t in Eq. 2 and k are the frequencies where these variables are evaluated. Analogously to the spatial domain, the previous equation can be written in a matrix form: \...
The immune system, on the other hand, has the more complex task of responding to ever evolving environmental components that enter the organism through different routes in the form of pathogens. This adaptation can occur through genetic recombination throughout life as in the case of antibody forma...
Abnormally shaped erythrocyte may present itself in the form of nondiscocytic, stomatocytic or cup formed erythrocyte [18]. Additionally, reductions in erythrocyte width and mass, and changes in platelet aggregation have also been detected in some CFS patients [13, 16]. Plasma proteins such as...
https://doi.org/10.1152/ajplung.00411.2014. Article CAS PubMed PubMed Central Google Scholar Shen Y, Wolkowicz MJ, Kotova T, Fan L, Timko MP. Transcriptome sequencing reveals e-cigarette vapor and mainstream-smoke from tobacco cigarettes activate different gene expression profiles in human ...
form of AD [82,119,176,184], however there are also genetic and environmental risk factors [120,217,219] that contribute to familial or sporadic forms of AD, respectively. The pathophysiology of AD is complex and not fully understood as we will see through the course of this review ...
Maier F, Zwicker S, Huckelhoven A, Meissner M, Funk J, Pfitzner AJP, Pfitzner UM: NONEXPRESSOR OF PATHOGENESIS-RELATED PROTEINS1 (NPR1) and some NPR1-related proteins are sensitive to salicylic acid. Mol Plant Pathol. 2011, 12 (1): 73-91. 10.1111/j.1364-3703.2010.00653.x. Article Pub...