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assistant to Mr Fuller & Mr Form (3 episodes, 2014) John Reynolds ... payroll accountant (3 episodes, 2014) Adrian Rozas Cristino ... production assistant (3 episodes, 2016-2017) Dakota Gerard ... office production assistant (3 episodes, 2016) Yumi Mizui ... translator/dialect coac...
The 29th Annual San Luis Obispo International Film Festival (April 25-30) announced this year’s robust film lineup, led by the Opening Night selection of Matt Johnson’s BlackBerry and the Closing Night selection of Marvin Samel’s IMordecai. Also on tap are the return of SLO Film Fest’...
The treatment of one patient with advanced EGFR T790M-positive NSCLC was described as proof of principle. Moreover, we found that hyperphosphorylation of Ack1 and the subsequent activation of antiapoptotic signaling via the AKT pathway contributed to ASK120067 resistance. Concomitant targeting of EGFR ...
The human gastrointestinal tract harbors complex and diverse microbes that act as a key factor in maintaining the homeostasis of the intestinal microenvironment [1]. It is estimated that approximately 1013–1014 bacterial cells from more than 1000 different species are present in gut, which form a ...
Contamination of heavy metals and antibiotics would threaten the water and soil resources. Phytoremediation can be potentially used to remediate metal and antibiotics contaminated sites. The current study was carried out over a period of 12 months t
(hdrD) to form the energy-converting ferredoxin:heterodisulfide oxidoreductase complex (Fig.4). Moreover, Methanomassiliicoccales possessed a large amount of methyl viologen-dependent hydrogenase (mvhADG) and the Hdr complex (hdrABC) to couple the reduction of the heterodisulfide CoM-S-S-CoB...
CXCL16 is synthesized as a transmembrane multi-domain molecule, with a soluble version generated by cleavage of the transmembrane form through the actions of cell-surface proteases, such as a disintegrin and metalloproteinase (ADAM) 10 and 17 [18,19,20]. CXCL16 is expressed in low levels by ...
In our present study, molecular docking results showed that curculigoside and orcinol glucoside have a strong binding ability to the hub targets (i.e., MMP9, JUN, and PTGS2) in the form of hydrogen bonds. PPI network analysis results indicated that MMP9, JUN, PTGS2, BDNF, and PTPRC we...
Understanding the mechanistic effects of novel immunotherapy agents is critical to improving their successful clinical translation. These effects need to be studied in preclinical models that maintain the heterogenous tumor microenvironment (TME) and dys