One of the leading current trends in technology is the miniaturization of devices to the microscale and nanoscale. The highly advanced approaches are based on biological systems, subjected to bioengineering using chemical, enzymatic and recombinant metho
Jian Yun Qing Hua Decoction (JYQHD), a traditional Chinese medicine decoction, which has been applied in the treatment of gastric cancer (GC). We attempt to confirm the anti-gastric cancer effect of JYQHD and explore the mechanism of JYQHD. Acute toxicit
Representation of the human kallikrein-kinin system in plasma and tissue and identified drug targets. ACE: Angiotensin-converting enzyme, B1R: Bradykinin B1 receptor, B2R: Bradykinin B2 receptor, BK: Bradykinin, BK 1–8: Bradykinin 1–8, C1INH: C1 esterase inhibitor, ERT: Enzyme replacement the...
Fermented milk intake was unrelated to the risk of IHD in both women and men. Non-fermented milk intake was associated in different directions with circulating levels of ACE2 and FGF21 in women—two essential cardiometabolic proteins, also related to IHD in women in our study....
Taohong Siwu Decoction (THSWD) is a prescription which included in the “List of Ancient Classic Prescriptions (First Batch)” issued by the National Administration of Traditional Chinese Medicine (TCM) and the National Medical Products Administration of
Cell cycle progression is primarily controlled by a family of cyclin-dependent kinases that can be negatively regulated by CDK inhibitor p21 WAF1[14]. In many cases, p21 WAF1 activity is coupled with the histone acetylation at the promoter level [18]. The novelty of plant chrysin is to delo...
drugs, biomolecules, and other agents [91]. The shell predominantly consists of lipids, proteins, or polymers, thereby safeguarding the encapsulated core. Polymer micelles form due to the uneven distribution of hydrophilic and hydrophobic properties of the polymer molecules. The hydrophobic segments of...
3E, the tissue level of BBR in the BM group was significantly higher than that in the free BBR group. We speculate that BM was more readily endocytosed by intestinal epithelial cells than by free BBR. Other studies have shown that MAG can serve as a potential inhibitor of P-glycoprotein ...
(5′-GTGATCTTTGACTC-3′) and − 4380 to − 4358 bp (5′-ATGTACTTTGCTCT-3′) regions of the ACE2 promoter [35] (Fig.2, Table1). HNF4α and ACE2 mRNA levels are simultaneously decreased by treatment of the calcineurin inhibitor cyclosporine in human HepG2 cells [35], ...
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