The deformability plot indicated the flexible region of the complexes in the form of peaks (Figs. 5B and 6B). The B-factor represented atomic positional changes in the flexible region of the docked complexes (Figs. 5C and 6C). The eigenvalue of the PVAO-TLR4 complex was 2.090283e-05 and...
Gli1(+) mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. Nat Cell Biol. 2020;22(11):1295–306. https://doi.org/10.1038/s41556-020-00591-9. Article CAS PubMed PubMed Central Google Scholar Rao W, Wang S, Duleba M, ...
Rodents are mostly used to develop models of pancreatitis. In mice and rats, AP in the form of acute inflammation with hemorrhage, when severe, can be induced by injections of caerulein, bile salt infusion, alcohol, duct obstruction, and a choline-deficient ethionine-supplemented (CDE) diet,...
In addition to the high immune heterogeneity of tumor cells, the heterogeneity of other cell types further increases the complexity of tumor tissue. These different types of cells form a complex interaction network through ligand-receptor interaction, paracrine, autocrine, and other intercellular ...
Predicted three-dimensional structures of EgANXB2 (A), EgANXB18 (B), EgANXB20 (C), and EgANXB23 (D). C, C terminal; N, N terminal. The Ca-binding sites were indicated, and EgANXB23 was predicted to form a dimer Full size image ...
In metazoans, members of the MCM family 2–7 form a hexamer complex at the DNA replication fork, which determines the initiation of DNA replication [93]. After NaCr treatment, the MCM protein in chromatin decreases significantly, and MCM3 is crotonylated [49], which indicates that DNA replica...
The inclusion criteria were: ‘papers on artificial intelligence, remote sensing, climate-smart agriculture’, ‘papers in the form of peer reviewed published scientific papers (journal/conference)’, and ‘papers published in 2011–2024’. The exclusion criteria were: ‘papers not related to ...
different functional elements and help optimize the vaccine’s overall design. AAY linkers, specific HEYGAEALERAG linkerGPGPG linkers, KK linkers and EAAAK linkers are used to bond Bcell, CLT and HLT epitopes. Also,HβD-3 and PADRE are used as adjuvants in the N-terminal of the ...
a common theme that emerges is that most editing occurs in non-coding regions of the transcriptome, even in cephalopods where recoding events are more prevalent than other organisms. Repetitive elements are particularly susceptible to editing because they often exist as inverted pairs and form ideal ...
3 ratio while retaining the proportion of positive and negative samples during the partitioning process. The larger sets for each species were merged to form the training dataset and the smaller sets for each species were merged to form the test dataset. The training dataset totaled 41,114 ...