The heat map shows the distribution of these lipids between individuals of the NDR and DR groups (Fig. 1C). The results of ROC analysis and the odds ratios of the lipid markers in the basic logistic regression models are shown in Table 2. The AUC values for the 15 lipids ranged from ...
SSC2: 66.75-74.62 Mb for TC, LDL-C and HDL-C/LDL-C, and SSC4: 119.87 Mb for TG overlapped with the previously reported QTL for blood lipids in a White Duroc × Erhualian F2 resource population, a commercial Duroc line and a Duroc × Pietrain F2 population [21, 28, 29]...
Insulin tolerance test To evaluate effect of palmitoleic acid on insulin sensitivity, an insulin tolerance test was performed on day 22. Following 5 h of food deprivation, an insulin solution (0.5 U/kg body weigh, Humulin R U-100, Eli Lilly, Japan) was administered subcutaneously. Blood sample...
In another clinical trial (NCT03340935), fasting-mimicking diet reduced blood glucose and growth factor concentration with reliable safety. [321]. Recently, a pilot clinical study (NCT04247464) is undergoing in Madrid, Spain to test whether short-term fasting (24 h before and 24 h after ...
blood lipids, or B-ultrasound results, with only two trials reporting liver biopsy results [20,122]. Furthermore, most investigations lasted less than 6 months, with only two studies having a 3-month follow-up [86,111]. It is important to note that liver biopsy is the gold standard for...
Samples were obtained after 12 h of fasting. Blood samples were obtained by jugular venipuncture after the saliva collection. In brief, saliva was obtained by introducing a sponge into the dog’s mouth for one to two minutes until wet and then placed into a Salivette tube (Salivette, Sarste...
Genetics of blood lipids among 300,000 multi-ethnic participants of the Million Veteran Program. Nat Genet. 2018;50:1514–23. Article CAS PubMed PubMed Central Google Scholar Surakka I, Horikoshi M, Mägi R, Sarin A-P, Mahajan A, Lagou V, et al. The impact of low-frequency and ...
A Fasting blood glucose levels and body weight in db/db mice and db/ + controls at 6, 10 and 14 weeks of age. n = 4–5 mice per group. ** and *** indicate p < 0.01 and p < 0.001, respectively, for db/db vs. db/ + controls at the specified time...
We will collect blood samples to assess outcomes such as HbA1c, high-sensitivity C-reactive protein, lipids, bone turnover markers, and insulin resistance. However, there will be no storage of biological samples. Interventions Explanation for the choice of comparators {6b} We will compare two ea...
Plasma lipids/lipoproteins and glucose were determined by established methodologies. C-reactive protein (CRP) and liver function tests (ALT, AST and GGT), as well as the full hematological profile (red blood cells, hematocrit and leukocyte formula) were determined. HbA1c was measured by ion-...