Site description and sampling As described in previous publications [1,2,3,4], the GH springs emerge in approximately 40 outlets across a 300-m length of the Expedition River bank, 2.5 km downstream from the White and Thompson glaciers. This region experiences seasonal darkness from ~ Octo...
Adolescent depression is becoming one of the major public health concerns, because of its increased prevalence and risk of significant functional impairment and suicidality. Clinical depression commonly emerges in adolescence; therefore, the prevention a
Multiple analysis to test the association between PCSK9 concentrations and BDI-II was adjusted for a priori covariates (age, gender, BMI, smoking habit, antidepressant treatment) and for variables that were significantly related with PCSK9 in univariate analysis (P value < 0.05). Given the ...
The goal of the present study was to investigate the effects of TAK-242 on the gut microbiota and the TLR4/JAK2/STAT3 signaling pathway in mice with dextran sulfate sodium (DSS)-induced colitis. At the phylum level, Bacteroidetes, Firmicutes, Actinobacte
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Reprints and permissions...
This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Reprints and ...
while Group 4 showed the highest male-to-female ratio of 5:1. Group 4 also had the highest metastatic rate among the four groups. Histological type was significantly associated with molecular group (p < 0.001, Chi squared test), with 90% (26/29) of desmoplastic/nodular tumours belongin...
(Fig.6b). Using three different predictors, we found that degron-related mutations are more likely to function as cancer drivers (Fig.6e). As degron-enriched proteins tend to be short-lived proteins (Fig.5a) that regulate metabolism, cell proliferation, and differentiation (Additional file1: ...
Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in an...
(Cliff’s delta of 0.574). Moreover, the Wilcoxon rank sum test provided a significant result with a q-value of 1.22e-111, suggesting that the S value could be more indicative of the type of bacteria commonly observed in the BE compared to other genomic features described previously (...