The implementation of in vivo pre-targeted technology is an efficient approach to avoid the prolonged circulation of radionuclides with the carrier in the body, thereby expanding the spectrum of radionuclide applications. Furthermore, this strategy potentiates the differentiation of diagnostic and ...
In general, the relationship between body size and cell size is controversial and complicated by the different use of cell volume, cell cross sectional area, or cell diameter [16, 17]. Only a few publications describe approaches for the histological evaluation of cardiac muscle. One study ...
Cells were mixed with appropriately diluted labeled antibodies at a 1:100 dilution (anti-C-KIT coupled with Alexa Fluor 647 Conjugate; Alexa Fluor 488 anti-CD31, Additional file 1: Table S1) incubated at 4 °C for 30 min. All samples were analyzed by a BD Accuri C6 flow cytometer (BD ...
Throughout the experiment, weight gain did not differ significantly among the three groups (P > 0.05) (Fig.6A-B). To investigate the effects of HME and BME on muscle mass in mice after injection, we assessed each group’s skeletal muscle-to-body weight ratio. We observed a significan...
Interestingly, over 90% of 5-HT in the body is produced in the gut, particularly in enterochromaffin cells (ECs); therefore, playing an indispensable role in the gut-brain axis. Noteworthily, increasing reports indicate that the influence of the Trp pathway exceeds the traditional focus on its...
Both ANP and BNP are the important hormones in activating pGC-A in body fluid, blood pressure and cardiac homeostasis13,16,17. The ANP/pGC-A signaling pathway lowers blood volume and blood pressure by increasing sodium/water excretion, vasorelaxation of vascular smooth muscle cells, increasing ...
used scRNA-seq, spatial transcriptomics methods, and CODEX to study specimens collected from 25 muscle-invasive bladder cancer patients [102]. From the single-cell clustering data, they discovered a novel biomarker, N-Cadherin 2 (encoded by CDH12), which is indicative of a cancerous epithelium ...
Transcripts associated with innate immunity are indicated with red circles and a subset of those are labeled with transcript symbols for the specific mRNA isoform difference. The axes correspond to: a Benjamini-Hochberg (False Discovery Rate (FDR) < 0.05) adjusted p-value (qval) and a Wald...
error of 0.04. The strongest correlation was observed between MaxArea and the percentage of muscle, with a coefficient of −0.21 (0.016). Our analysis did not reveal any significant associations between the resilience indicators and the percentage of backfat, intramuscular fat, or final body ...
, and bioluminescence was detected after five days.KLNP-M delivers pGFP intramuscularly into mice.L-NLNP-M delivers pSpike into mice. Spike expression in muscle tissues was detected using Western blot, serum levels of IL-6 and TNF-α assessed by ELISA, and body weights measured every three...