Brown EJ, Pollak MR, Barua M (2014) Genetic testing for nephrotic syndrome and FSGS in the era of next-generation sequencing. Kidney Int 85:1030–1038 CentralBrown EJ, Pollak MR, Barua M. Genetic testing for nephrotic syndrome and FSGS in the era of next-generation sequencing. Kidney Int...
种组织学病变,而非一种疾病,其是成人和儿童肾病综合征常见的基础病变,特别是在美国、巴西和许多其他国家[参考文献1、Haas M, Meehan SM, Karrison TG, Spargo BH. Changing etiologies of unexplained adult nephrotic syndrome: a comparison of renal biopsy findings...
参考文献 SIM J J, SMOYER W E, SCHACHTER A D. Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are a spectrum of a single disease within immune-mediated nephrotic syndrome[J/OL]. Kidney360, 2024. [2024-7-9].https://journals.lww.com/kidney360/citation/9900/minim...
Focal segmental glomerulosclerosis (FSGS) is the most common glomerular disorder that causes ESRD in the USA27and commonly presents with nephrotic syndrome,28which increases the risk of pregnancy complications. 在美国 局灶节段性肾小球硬化(FSGS)是最常见的引发ES...
(MCD) and focal segmental glomerulosclerosis (FSGS) are a spectrum of a single disease within immune-mediated nephrotic syndrome[J/OL]. Kidney360, 2024. [2024-7-9].https://journals.lww.com/kidney360/citation/9900/minimal_change_disease__mcd__and_focal_segmental.425.aspx. DOI: 10.34067/KID...
FSGS被发现是遗传性肾病综合征中最常见的病理类型,随着基因检测的普及和检测费用的降低,目前已知致病基因已超过50个[2],有研究发现在25岁前患激素抵抗型肾病综合征(steroid-resistant nephrotic syndrome, SRNS)家系中有29.5%发现了单基因变异[3],主要与编码足细胞功能或结构蛋白的基因突变相关。遗传性FSGS可存在于儿...
FSGS被发现是遗传性肾病综合征中最常见的病理类型,随着基因检测的普及和检测费用的降低,目前已知致病基因已超过50个[2],有研究发现在25岁前患激素抵抗型肾病综合征(steroid-resistant nephrotic syndrome, SRNS)家系中有29.5%发现了单基因变异[3],主要与编码足细胞功能或结构蛋白的基因突变相关。遗传性FSGS可存在于儿...
2. Gbadegesin RA, Lavin PJ, Hall G, et al. Inverted formin 2 mutations with variable expression in patients with sporadic and hereditary focal and segmental glomerulosclerosis. Kidney Int 2012; 81:94. 3. Hinkes BG, Mucha B, Vlangos CN, et al. Nephrotic syndrome in the first year of ...
[4]Ding WY, Koziell A, McCarthy HJ, et al. Initial steroid sensitivity in children with steroid-resistant nephrotic syndrome predicts post-transplant recurrence. J Am Soc Nephrol 2014; 25:1342. [5]Pascual J, Mezrich JD, Djamali A, et al. Alemtuzumab induction and recurrence of glomerular...
Carraro M, Caridi G, Bruschi M, et al. Serum glomerular permeability activity in patients with podocin mutations (NPHS2) and steroid-resistant nephrotic syndrome. J Am Soc Nephrol 2002; 13:1946. Bertelli R, Ginevri F, Caridi G, et al. Recurrence of focal segmental glomerulosclerosis after re...