Population level data support that consumption of fructose and fructose-based sweeteners has dramatically increased and suggest that high dietary intake of fructose is an important factor in the development of the cardiorenal metabolic syndrome (CRS). The CRS is a constellation of cardiac, kidney and...
Function:Fructose(Fru) is used as an energy fuel and for the synthesis ofglycoproteinsandglycolipids. Food sources: Most Fru is consumed with high-fructose corn syrup, refined sugar (sucrose), fruits, and vegetables. Requirements: No dietary Fru is needed since the required amounts are modest ...
(h) CaSki cell number as a function of PF-06835919 concentration (n = 3 per dose). Cells were cultured with 10 mM glucose and 10 mM fructose. (i) Total fructose 1-phosphate from CaSki cells after treatment with vehicle (n = 3), 30 µM (n = 3), or 250...
probability calculator sample size calculator slope calculator area of a circle calculator circumference calculator combination calculator inverse matrix calculator mod calculator pythagorean theorem calculator confidence interval calculator double integral calculator matrix multiplication calculator inverse function ...
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
2023, Nature Cell Biology Tetrazine bioorthogonal chemistry derived in vivo imaging 2022, Frontiers in Molecular Biosciences A non-metabolic function of hexokinase 2 in small cell lung cancer: promotes cancer cell stemness by increasing USP11-mediated CD133 stability 2022, Cancer Communications Therapeuti...
A significantly smaller rise in blood glucose concentrations (increase from baseline: glucose+lipids P<0.001 vs fructose+lipids n.s.) suggested that fructose had a small effect, if any at all, on glucose metabolism. Serum insulin activity showed significant differences as a function of carbohydrate...
Importantly, instead of binding fructose, KHK-A interacts with the rate-limiting enzyme phosphoribosyl pyrophosphate synthetase 1 (PRPS1) in the de novo nucleic acid synthesis pathway. This allows KHK-A to function as a protein kinase and directly phosphorylate PRPS1 at Thr225 (Km ∼0.2 μM)...
(Froesch et al 1957, 1963), it is clear that disturbed function of the kidney contributes importantly to the manifestations of this nutritional disease (Perheentupa et al 1962, Lelong et al 1962, Cornblath et al 1963, Mass et al 1966, Levin et al 1963, 1968, Lamière et...