Background: Fructose-1,6-bisphosphatase (FBPase) deficiency is a rare disorder of glucose metabolism, mainly revealed by hypoglycemia and lactic acidosis. The disease is caused by a mutation of FBP1 gene, which
Here we demonstrate that telomerase activity is differentially regulated in cancer and normal cells depending on the expression status of fructose-1,6-bisphosphatase 1 (FBP1). In FBP1-expressing cells, FBP1 directly interacts with and dephosphorylates telomerase reverse transcriptase (TERT) at Ser227...
Fructose 1,6-bisphosphatase (EC 3.1.3.11) is a key enzyme in glycolysis and catalyses the hydrolysis of D-fructose 1,6-bisphosphate to D-fructose 6-phosphate and inorganic phosphate. From:Plant Physiology and Biochemistry,2021 Also in subject area: ...
果糖1,6二磷酸酶缺乏症(Fructose-1,6-bisphosphatase deficiency)是一种罕见的常染色体隐性遗传病,于1970年由Baker首先报道。由于FBP1基因突变导致肝脏的果糖1,6二磷酸酶缺乏或活性低下,造成1, 6二磷酸果糖不能转化为6-磷酸果糖,影响...
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improved and no appreciable loss of activity was measured even when the partially purifiedFBPase (Fraction I FBPases of the castor bean endosperm and leaf properties and partialpurification. Arch. The study of spinach leaf chloroplast fructose- 1,6-bisphosphatase (FBPase). Bryopsis corticulansChloroph...
Fructose 1,6-bisphosphatase-1 Inhibitor详情 评价(0) 货号:ajci17648 CAS:883973-99-7 别名:F1,6BPase-1 Inhibitor|FBP1 Inhibitor|FBPase-1 Inhibitor 分子式:C13H7Cl3N2O3S 分子量:377.6 纯度:>98% 溶解度:≤14mg/ml in DMSO;20mg/ml in dimethyl formamide ...
A rate-limiting step in gluconeogenesis is the conversion of fructose 1,6- bisphosphate to fructose 6-phosphate by a fructose bisphosphatase (FBPase). The Mtb genome contains only one annotated FBPase gene, glpX. Here we show that, unexpectedly, an Mtb mutant lacking GLPX grows on ...
英文名称:cFBPase | cytosolic fructose-1,6-bisphosphatase (cytoplasm marker in photosynthetic tissues))总访问:424 国产/进口:进口半年访问:20 产地/品牌:瑞典Agrisera产品类别:免疫学/诊断检测试剂 规格:AS04 043最后更新:2024-12-5 货号: CAS 号: ...
The present invention relates to certain substituted piperazines, which exhibit inhibitory action against fructose-1,6-bisphosphatase (FBPase). These compounds are indicated in the treatment or management of Type-II diabetes. BACKGROUND Diabetes is a major international health problem, affecting 100 mill...