不同学科领域,不同期刊,差异巨大 例如,Frontier in Immunology (免疫学前沿) 和 Frontier in Neuroscience (神经科学前沿) 通常被认为是其领域内较有影响力的期刊,其影响因子也相对较高。 这主要是因为免疫学和神经科学是当前热门的研究领域,大量的研究成果涌现,也吸引了更多高质量的投稿,从而提升了期刊的影响因子和...
Cellular immunity plays a central role in anti-tumor responses. DCs, as the most efficient APCs, capture tumor antigens and display them to T cells using MHC molecules, initiating T cell-mediated tumor destruction [118]. Immature DCs originate from progenitor cells in the bone marrow. Through ...
After several decades, therapeutic cancer vaccines now show signs of efficacy and potential to help patients resistant to other standard-of-care immunotherapies, but they have yet to realize their full potential and expand the oncologic armamentarium. He
Virchow found the connection between tumors and intratumoral inflammation [35]. In 1891, William Coley, the father of cancer immunology, used Coley toxins to cure the first case of
iRT has yet to achieve groundbreaking progress, however, numerous issues remain to be resolved in future. Primarily, the abscopal effect was predominantly recognized, yet the impact of iRT on the TME and the potential mechanism by which it induces abscopal effects on tumors remains elusive [25,...
Trends in Microbiology May 2022 10被引用 0笔记 开学季特惠,9月3日-11月30日,专业版用户每周AI豆3倍膨胀,快来领取吧! 摘要原文 Microbial metabolites mediate the impact of the microbiome on host physiology. Here, we highlight metabolites of interest for early-life programming and synthesise early evi...
These results suggest that caspase-orchestrated mitochondrial events determine the impact of apoptotic cells on the immune response. This meeting gave a succinct update on mechanistic and translational aspects of cell death regulation in cancer covering topics within immunology, neurology and oncology as ...
After several decades, therapeutic cancer vaccines now show signs of efficacy and potential to help patients resistant to other standard-of-care immunotherapies, but they have yet to realize their full potential and expand the oncologic armamentarium. He
The presence of tumors that harbor mutations in specific genes can influence therapy decisions. For example, the use of epidermal growth factor receptor (EGFR) TKIs is standard of care in patients with EGFR-mutation-positive NSCLC [92–94], and studies suggest that this population may not ...
In a multivariate model, MSM was the only variable that remained associated with reporting anonymous sex as a risk factor at the time of infection (OR 3.4 CI: 1.9–6.0; p < 0.0001). However, the proportion of MSM who reported anonymous sex was similar to that of individuals who were...