[2]. HIV encephalitis and consequent neuronal injury has been studied by a number of laboratories and it is clear that virus infection, macrophage/microglial activation, as well as macrophage transmigration of the blood brain barrier are important in the disease progress. It has been poorly ...
Human microorganisms, including bacteria, fungi, and viruses, play key roles in several physiological and pathological processes. Some studies discovered that tumour tissues once considered sterile actually host a variety of microorganisms, which have be
Tumor immunotherapy has a history of more than 100 years [34]. In 1796, Edward Jenner used a vaccine to treat smallpox patients, which laid the immunological foundation for immunotherapy. In 1863, Virchow found the connection between tumors and intratumoral inflammation [35]. In 1891, William C...
immunogenic cell death, apoptosis, pyroptosis, necroptosis, parthanatos, netotic cell death, cuproptosis, lysosomal-dependent cell death, autophagy-dependent cell death and mpt-driven necrosis, all of which belong to programmed cell death. In this review, we briefly...
and business development experience in the biotechnology industry to Todos. Mr. Meiselbach will focus on liaising with governments regarding the deployment of Tollovir™, Tollovid® and Videssa®. “We see significant potential to bring Tollovir to governments as a key solution for hospital ...
disease screening and early detection, diagnosis, prognosis, therapeutic prediction, and disease monitoring. Cancers are heterogeneous at every level, including molecular and cellular variations, histopathology, and clinical manifestations, which makes biomarker discovery an essential need for the vision of ...
The immune system defends the organism against harmful infection, damage, or stress by using processes of resistance or tolerance. New research reveals that the immune system can control behavior in addition to its usual functions, underscoring its neglected function as a neuromodulator [5,15,16,...
The use of modulator drugs that target the Cystic Fibrosis transmembrane conductance regulator (CFTR) is the final frontier in the treatment of Cystic Fibrosis (CF), a genetic multiorgan disease. F508del is the most common mutation causing defective form
Many cells die in a specific time in our body because they are aging, infected or damaged. The defects can negatively influence the cell development and ultimately lead to a variety of diseases, including autoimmune diseases, cancer or infection [4]. Cell death is not only a physiological ...
Unlike infection of hepatitis B virus (HBV), HCV infection is a multifaceted disease with both hepatic and extrahepatic manifestations3, and HCV can reside at non-hepatic cells4-6, which may play a role in viral persistence and reactivation. However, in vitro systems to investigate the ...