11.The Significance of Serum Total PSA and Free Versus Total PSA in Diagnosis of Prostate Malignant and Benignant Diseases血清T-PSA与F/T比值对前列腺良、恶性病变的鉴别诊断价值 12.Significance of serum PSA,F-PSA/T-PSA ratio in diagnosis of prostate cancer血清总前列腺特异抗原及其F/T比值对前列腺...
Nevertheless, at early stages, PSA assay has a low specificity: rather than a tumor marker, it has to be considered as a prostate (i.e. malignant and benign diseases) marker. In order to evaluate the contribution of free PSA versus total PSA we tested 197 men (>44 years) with RIACT ...
( = 0. 37) and BPH ( = 0. 61).By contrast, the f/tPSA ratio showed significant between-group differences (PCa versus prostatitis ( = 0. 011), PCa versus BPH ( = 0.0001).Conclusions:Chronic asymptomatic prostatitis NIH category IV has similar effects on total PSA and free PSA levels...
Statistically significant differences but weak correlations were observed between the individual f-PSA, c-PSA, and t-PSA concentrations with regard to pathologic stage (organ-confined versus extraprostatic) and grade. No significant relationship, however, was observed with the three ratios. Higher PSA...
All patients were rebiopsied to determine the receiver operating characteristics of total PSA versus percent free PSA for prostate cancer detection. RESULTS: The study biopsy identified 11 prostate cancer cases. The median percent free PSA was significantly higher at 18.0% among men without prostate ...
Receiver operating characteristic (ROC) curves for each group were generated by plotting the sensitivity versus 1-specificity for the f/t PSA ratio. The sensitivity, specificity, positive likelihood ratio (PLR), and negative likelihood ratio (NLR) were obtained using variousf/t PSA ratio cutoffs ...
Free-to-Total Prostate Specific Antigen Ratio as a Single Test for Detection of Significant Stage T1c Prostate Cancer RESULTS: Benign prostatic hypertrophy had a greater median free-to-total PSA ratio than stages T1c and T2 or greater prostate cancer (0.16 versus 0.09 ......
PSA can be reliably measured in the serum in two major isoforms: PSA complexed to alpha1-antichymotrypsin and uncomplexed free PSA (fPSA). Multiple investigations have illustrated the usefulness of the free/total PSA proportion (percent fPSA) in differentiating prostate cancer from benign prostate ...
Comparison of PSA relapse-free survival in patients treated with ultra-high-dose IMRT versus combination HDR brachytherapy and IMRT. Brachytherapy. 2010;9(4):313-318.Deutsch I, Zelefsky MJ, Zhang Z, et al. Comparison of PSA relapse- free survival in patients treated with ultra-high-dose ...
While progression-free survival was strongly in favor of the association with a 46% reduction in the risk of progression or death (HR = 0.54; 95% CI: [0.36–0.79]; p < 0.0015), PFS of 16.4 months versus 9.8 months and excellent tolerability, the results of 47-month overall survival...