Liu Y,Long J,Liu J.Mitochondrial free radical theory of aging:who moved my premise[J].Geriatr Gerontol Int,2014,14(4):740-749.Barja G. The mitochondrial free radical theory of aging. Prog Mol Biol Transl Sci 2014; 127: 1-27.
The free-radical theory of aging was formally proposed by Denham Harman in 1956 and postulates that the inborn process of aging is caused by cumulative oxidative damage to cells by free radicals produced during aerobic respiration. Free radicals are atoms or molecules with single unpaired electrons....
Free radical theory of aging: inhi- bition of amyloidosis in mice by antioxidants; possible mechanism. J Am Geriatr Soc. 1976; 24(5):203.Harman D, Eddy DE, Noffsinger J (1976) Free radical theory of aging: inhibition of amyloidosis in mice by antioxidants: possible mechanism. J Am ...
Though phenomenal literature and huge theories of ageing are put forward, the most recent and highly accepted theory is "Free Radical Theory of Ageing" conceived by Harman.[1] In the free radical theory of aging, there is some imbalance between production and scavenging mechanisms of free radica...
在介绍自由基导致衰老的理论中,教授介绍道:free radicals cause damage to other molecules and structures within the cell,including,most significantly,to the cell’s DNA,即自由基损坏分子和细胞DNA,导致了衰老,因此B选项是正确答案。抗氧化剂的作用是使自由基稳定从而使细胞不受损害,因此并不是破坏细胞结构,也...
提出衰老的自由基学说(Free radical theory of aging)以来,越来越多的实验证实,呼吸着的细胞不断产生的氧自由基及其氧化反 … doctor.51daifu.com|基于5个网页 2. 自由基理论 讨论课我做的是自由基理论(free radical theory of aging),材料里讲完自由基反应和MDA产生于堆积跟衰老的关系之后,加… ...
chemicals. Free radicals may cause schizophrenia, Alzheimer’s disease, Parkinson’s disease, and deafness. Another example of free radical damage is the skin damage that occurs with excessive sun exposure. The “free radicaltheoryof aging” proposes that free radicals trigger the aging process ...
This idea that damage by reactive oxygen species contributes to age-related deterioration formed the basis for Harman's Mitochondrial Free Radical Theory of Aging. Harman's theory was later supported by a large body of evidence suggesting that free radicals do play an important role in aging. As...
...的老化过程 老化过程中仍维持心理健康 75 有关自由基理论(Free-Radical Theory)的叙述下列何者正确? xuelele.com.tw|基于4个网页 2. 科学研究 ...基(free-radicals)的活动能力,而一些科学研究(Free-Radical Theory)认为自由基就是癌症和身体衰老的原因之一,由此 … ...
Harman D. Free radical theory of aging: role of free radicals in the origination and evolution of life, aging, and disease processes. In Johnson et al. (Eds) Free radicals, aging, and degenerative diseases, pp. 3–49, Alan R. Liss, New York, 1986 ...