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you use just three or four samples and then mangle them to death instead of using 100 different samples from all over the place. You can be sure that they share a common "timbre signature" and its not limiting at all. I found that I can make a whole drum kit out of one simple ...
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Cell-free biology is the activation of biological processes without the use of intact living cells. It has been used for more than 50 years across the life sciences as a foundational research tool, but a recent technical renaissance has facilitated high-
Entire reconstitution of tRNAs for active protein production in a cell-free system brings flexibility into the genetic code engineering. It can also contribute to the field of cell-free synthetic biology, which aims to construct self-replicable artificia
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Sepsis remains an unacceptably high mortality due to the lack of biomarkers for predicting septic outcomes in the early period. Mitochondrial redox states play a pivotal role in this condition and are disturbed early in the development of sepsis. Here, we hypothesized that visualizing mitochondrial re...
All samples were bisulfite converted using EZ DNA Methylation Kit (Zymo, USA) per the manufacturer’s standardized method. Illumina Infinium MethylationEPIC BeadChip arrays (~ 850,000 CpG loci genome-wide) was used for methylation analysis based on manufacturer’s standardized protocol20. Data pre...
We introduce UniCell: Deconvolve Base (UCDBase), a pre-trained, interpretable, deep learning model to deconvolve cell type fractions and predict cell identity across Spatial, bulk-RNA-Seq, and scRNA-Seq datasets without contextualized reference data. UCD