Also Known As: Free Light Chains, SFLC, FLC, Kappa and Lambda Free Light Chains, Quantitative Serum Free Light Chains with Ratio Board Approved At a Glance Why Get Tested? To help detect, diagnose, and monitor plasma cell disorders (dyscrasias) such as multiple myeloma, primary amyloidosis,...
Conclusion: Serum-free light chains should be requested when there is a high index of clinical suspicion. Neither SFLC nor SPE should be performed in isolation when screening patients for monoclonal gammopathy, to ensure that no patient is missed. What this study adds: The s...
Ressources | Current Status of Detecting Monoclonal Antibodies and Free Light Chains in Serum | Deutschland
Serum free light chains: an alternative to the urine Bence Jones proteins screening test for monoclonal gammopathies. Clin Chem. 2006;52(9):1743–8. Article CAS PubMed Google Scholar Dispenzieri A, Kyle R, Merlini G, Miguel JS, Ludwig H, Hajek R, et al. International Myeloma Working ...
1.The objective of this study was to explore the clinical significance of measuringserum free light chains(sFLC) and to compare with serum total light chains(free and binded) in multiple myeloma(MM).本研究测定多发性骨髓瘤(multiple myeloma,MM)患者血清游离轻链(serum free light chain,sFLC)数值,并...
Diagnosis and monitoring of multiple myeloma (MM) and related conditions are usually carried out by means of serum and urine protein electrophoresis and immunofixation. In the early 2000s, an assay aimed at evaluating serum free light chains (sFLCs) was made available and subsequently tested in ...
Objectives Testing of serum-free light chains kappa (κ) and lambda (λ), along with ratio (FLCR) is essential for the diagnosis and management of monoclonal gammopathies. Accurate clinical diagnosis depends upon appropriate local population reference in
A new immunoassay for free light chain measurements has been reported to be useful for the diagnosis and monitoring of monoclonal light chain diseases and nonsecretory myeloma. We describe experience with and some potential pitfalls of the assay.The assay was assessed for precision, sample type and...
Bermudo, CGarcia, J LMartin Ruiz, J ADuro Mill�n, RIglesias, M MRomero, F F
1) serum free light chains 血清游离轻链1. The objective of this study was to explore the clinical significance of measuring serum free light chains(sFLC) and to compare with serum total light chains(free and binded) in multiple myeloma(MM). 本研究测定多发性骨髓瘤(multiple myeloma,MM)患者...