Borderline high serum free light chain k/ ratios are seen not only in dialysis patients but also in non-dialysis-dependent renal impairment and inflammatory states. Am J Clin Pathol 2009; 132: 309.Marshall G, Tate J, Mollee P. Borderline high serum free light chain kappa/lambda ratios are...
The paper deals with examination of free kappa light chains (FKLC) in the cerebrospinal fluid and serum of patients with multiple sclerosis (MS). The patient group included 84 women (mean age 34.03 ± 10.33 years) and 24 men (mean age 33.81 ± 10.61 years). The average disease duration ...
Introduction Kappa and lambda free light chains (FLC) are a side product of immunoglobulin synthesis. They are small molecular weight proteins and are present in serum of healthy people. They are increased in various diseases with enhanced immunoglobulin production. Like other small molecular we...
Role of nephelometry-based detection of serum free light chain kappa/lambda in diagnosis of multiple myelomaZarabpouri, FPopov, JMontana, LFerruzza, A SNaides, S J
Kanui BRKappaKappa ESKappa FRKapsel - DEKapten & Son DEKARE DEKaren Millen UK & IEKariBoo BijouxKarl Lagerfeld (US)Karl Lagerfeld DEKarl Lagerfeld FRKarl Lagerfeld UKKarmacistKarneval-Universe DEkartenmachen DEKartenmacherei DEKartoffelshop DEKasanova IT...
Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains Clin Chem, 48 (2002), pp. 1437-1444 CrossrefView in ScopusGoogle Scholar 2 M Drayson, LX Tang, R Drew, GP Mead, H Carr-Smi...
In addition, butyrate-mediated activation of FFAR2 signaling in mice chondrocyte exhibit anti-inflammatory activity by inhibiting the phosphorylation of NFκB (nuclear factor kappa-light-chain-enhancer of activated B cells), MAPK, AMPK-α (5’ adenosine monophosphate-activated protein kinase), and ...
Morel et al., “Monoclonal Antibodies to Bovine Serum Albumin: Affinity and Specificity Determinations”, Mol. Immunol. 25(1):7 (1988). Nechansky et al., “Compensation of endogenous IgG mediated inhibition of antibody-dependent cellular cytotoxicity by glyco-engineering of therapeutic antibodies”...
in an ELISA assay. The ELISA assay is performed as follows. A 96 well microtiter plate is coated overnight at 4° C. using 50 μL/well of goat anti-human kappa polyclonal antibody diluted to 5 μg/mL in phosphate buffered saline (PBS). Following overnight incubation, the plate is aspi...
appear to be useful in AL amyloidosis (1, 2).OBJECTIVETo study the value of serum free light chains for the diagnosis of systemic AL amyloidosis and for monitoring effects of therapy.PATIENTS AND METHODSTwenty-two patients with AL-kappa and 53 with AL-lambda amyloidosis were studied at ...