Free light chains tests are used in the diagnosis and monitoring of light chain-associated amyloidosis and in monoclonal gammopathies such as multiple myeloma. Free kappa and lambda light chains are antibody fragments secreted by plasma cells in the bone marrow. Plasma cells secrete either kappa or...
Interestingly, in 1 patient with an abnormal FLC ratio and total kappa/lambda result had a lambda light chain identified using IFE.Comparisons between the performances of Freelite, Freelite + SPEP, Total kappa/lambda and total kappa/lambda + SPEP are shown in table...
Free light chains (FLC) or serum free light chains (SFLC) refer to those that are not part of whole (intact) immunoglobulins and are present in the blood. This test measures the amount of free kappa and lambda light chains in the blood and calculates a kappa/lambda ratio to help detect...
The paper deals with examination of free kappa light chains (FKLC) in the cerebrospinal fluid and serum of patients with multiple sclerosis (MS). The patient group included 84 women (mean age 34.03 ± 10.33 years) and 24 men (mean age 33.81 ± 10.61 years). The average disease duration ...
Sign up with one click: Facebook Twitter Google Share on Facebook KAP (redirected fromKAPS) Acronyms KAP Kernel Andorra Prolog. The predecessor ofAKL. ["Kernel Andorra Prolog and its Computation Model", S. Haridi <seif@sics.se> et al, in Logic Programming: Proc 7th Intl Conf, MIT Press...
The serum free light chain (FLC) assay quantitates free immunoglobulin kappa and lambda light chains, which has prognostic value in plasma cell dyscrasias... CA Thompson,MJ Maurer,JR Cerhan,... - 《American Journal of Hematology》 被引量: 42发表: 2011年 Serum free light chains as predictors...
There are two types of immunoglobulin light chain produced in humans, designated kappa (κ) and lambda (λ). The quantification of serum FLC is used as an aid in the diagnosis and monitoring patients with Multiple Myeloma. Ratio FLC value (kappa FLC/lambda FLC) compared to reference ranges ...
Levels of κ and λ serum free light chains and the κ/λ ratio were not different among IgG4-related disease (n = 45), Sjögren’s syndrome (n = 25) and sarcoidosis (n = 15) patients (median with interquantile range). Statistics performed by Kruskal–Wallis test. sFLC...
The free light chain (FLC) assay does quantify concentrations of free kappa and lambda immunoglobulin light chains in serum. The potential use of this diagnostic test for patients diagnosed with plasma cell dyscrasias includes, amongst others, primary diagnosis, prognosis, detection of relapse and mon...
kappa- the 10th letter of the Greek alphabet lambda- the 11th letter of the Greek alphabet mu- the 12th letter of the Greek alphabet nu- the 13th letter of the Greek alphabet xi- the 14th letter of the Greek alphabet omicron- the 15th letter of the Greek alphabet ...