CS and poly-L-lysine (PL) self-assemble to create positively charged nanoparticles (CS-PL), whereas TA coordinates with Ce3+ to form a metal-organic framework nanosystem (TA@Ce3+). The synergistic use of both aims to treat bacterial infections and repair oxidative stress environments, ...
[58] found that l-methionine derivatives can be incorporated into soy hydrolysates using papain to form plastein; the authors suggested the formation of peptide bonds during the reaction between the amino acids and protein hydrolysates. Condensation was not observed with free amino acids and was ...
Upon the infection, CRISPR array is transcribed, producing precursor-CRISPR RNA (pre-crRNA), which is further processed to form CRISPR RNA (crRNA). Later, for simple use and design, crRNA was engineered to form a single-guide RNA (sgRNA or gRNA). crRNA complementary to the foreign ...
Cell-free production of a functional oligomeric form of a Chlamydia major outer-membrane protein (MOMP) for vaccine development. J Biol Chem. 2017;292:15121–32. CAS PubMed PubMed Central Google Scholar Pichichero ME. Protein carriers of conjugate vaccines: characteristics, development, and ...
The accumulation of metHb, an oxidized form of cell-free Hb has been reported in other contexts to be cytotoxic. For instance, Kumar et al. reported that cell-free metHb has been found to drive platelets to apoptosis [39]. In malaria, metHb was found, in the presence of heme, to ...
Position 84 of the DPb subunit lines pocket 1 of the DP antigen-binding site, and is equivalent to position 86 of DRb.17 In DPb, residues 84–87 form a linked unit, which influences the size and charge of the amino-acid side chains of antigens preferred by pocket 1. Thus, the ...
Retroviral integration, the process of covalently inserting viral DNA into the host genome, is a point of no return in the replication cycle. Yet, strand transfer is intrinsically iso-energetic and it is not clear how efficient integration can be achieve
L. Shi, Y. Hu, M.W. Ullah, I. Ullah, H. Ou, W. Zhang, L. Xiong, X. Zhang Cryogenic free-form extrusion bioprinting of decellularized small intestinal submucosa for potential applications in skin tissue engineering Biofabrication (2019), p. 11, 10.1088/1758-5090/ab15a9 Google Scholar ...
Micro RNAs (miRNAs) and long non-coding RNAs (lncRNAs) have been proposed as biomarkers, and they have been repeatedly linked to some diseases, including human cancers. miRNAs-lncRNAs-mRNAs are interconnected and regulate each other to form functional network modules. Any abnormalities in their ...
15. The non-naturally occurring polypeptide of claim 1, wherein the non-naturally occurring polypeptide is monomeric. 16. The non-naturally occurring polypeptide of claim 1, wherein the non-naturally occurring polypeptide does not form a stable triple helix structure of a naturally occurring collage...