What is label-free screening and why use it in drug discovery? - European Pharmaceutical ReviewLabelfree screeningUniversity of Queensland
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The toxic effects of drugs may also take a variety of forms. Many drugs are toxic in large (nontherapeutic) doses. A few drugs (for example, certain antitumor preparations) have a teratogenic effect (that is, they cause defects in the development of the embryo). The teratogenic effect of...
The Inflation Reduction Act of 2022 has triggered a raft of changes to Medicare Part D plans and Medicare Advantage plans that affect prescription drug coverage in 2025. Here’s what to know. Elaine K. HowleyJan. 29, 2025 Medicare Coverage for Ambulance and ER ...
To date, drug discovery strategies for 3CLpro have largely focused on structure-based design and virtual screening efforts or limited high-throughput screening (HTS) of small molecules, including opportunities for repurposing approved drugs (Ghosh et al., 2007; Jin et al., 2020; Lee et al., ...
Cell-free biology is the activation of biological processes without the use of intact living cells. It has been used for more than 50 years across the life sciences as a foundational research tool, but a recent technical renaissance has facilitated high-
Candidate DDO SNPs screening and mRNA expression Data from 268 brains of nonpsychiatric individuals (176 males; mean age±s.d. 27.89±22.15 years; pH 6.53±0.3; postmortem interval: 26.37±17.11) were analyzed (Supplementary Table 1). These data were obtained from the largest postmortem collection...
resolidification (161,207–209). In the case of aiming at a controlled release formulation, the formation of a physical mixture between drug and lipid excipient might be the wrong path as the dissolution rate of the physical mixtures may be higher than that of the solidified melt-dispersion (...
In the current era of precision medicine, the identification of genomic alterations has revolutionised the management of patients with solid tumours. Recent advances in the detection and characterisation of circulating tumour DNA (ctDNA) have enabled the
Screening for Overweight and Obesity among School-Age Children and Adolescents; WS/T 586-2018; National Health and Family Planning Commission of the People’s China: Beijing, China, 2018. [Google Scholar] National Health and Family Planning Commission of the People’s Republic of China (Ed.) ...