The clinical trial roadmap is a free PowerPoint template that features all the 3 main phases necessary for any drug or procedure to receive approval from the FDA. Phase I is conducted on a small, healthy group of participants and aims to determine the safe dosage as well as uncover potential...
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The purified RNA served as template to generate cDNA using the SuperScript™ IV First-Strand Synthesis System (Invitrogen), and was subsequently turned into double-stranded DNA with the NEBNEXT® mRNA Second Strand Synthesis Module (New England Biolabs). The DNA was then purified using MagSi-...
The lysate was used as template for PCR amplification. To identify the species of taeniid egg, partial NADH dehydrogenase subunit 1 (nad1) gene was amplified by nested PCR, using the following primer pairs as outside and inside primers: forward-out 5′ -TGTTTTTGAGATCAGTTCGGTGTG-3′, ...
Hoffmann TC, Glasziou PP, Boutron I, Milne R, Perera R, Moher D, et al. Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide. BMJ. 2014;348(mar07 3):g1687. ArticlePubMedGoogle Scholar ...
We demonstrated the preparation of an artificial tubular structure using cell/nanosheet constructs by rolling the nanosheet with myoblasts around the template (for example, silicone tube, 3 mm diameter). The lateral image of the rolled myoblasts on the nanosheet showed a layered structure, and the ...
Recently, we showed that homologous nascent RNA can be used as a template for error-free repair of double-strand breaks (DSBs) in the transcribed genome and to restore the missing sequence at the break site via the transcription-coupled classical nonhomologous end-joining (TC-NHEJ) pathway. ...
3.1. Generation of BF: condensation of droplets as patterning template Elastomers, such as rubbers and silicones, are versatile materials that can be used for implantable medical devices (as reviewed in Ref. [34]). Elastomer surfaces might provide a favorable interface with the biological components...
The repair of DNA double-strand breaks (DSBs) involves interdependent molecular pathways, of which the choice is crucial for a cell’s fate when facing a damage. Growing evidence points toward the fact that DSB repair capacities correlate with disease ag
Merging the ligand core with a new R-group requires that both the linking atom on the template core and on the attachable R-group are specified. The merging is carried out with the RDKit editable molecule32. RDKit is further used to generate 3D conformers using the ETKDG method34. The ...