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inESR1andARID1Afor both cfDNA and tumor biopsies in 20 ER+/HER2− metastatic cancer patients when compared to 279 primary ER+/HER2− breast carcinomas published previously by The Cancer Genome Atlas (TCGA)25(Bonferroni-corrected Fisher’s exact test,p = 1.46 × 10−8and 2.58...
These methods require deep sequencing that significantly increases the cost and difficulty to use in clinical practice. Chromosomal instability analysis in cell-free DNA by low-coverage whole-genome sequencing was used for the primary diagnosis of ovarian cancer21. In prenatal testing, several studies ...
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However, the solely usable crystal in practice, KBe2BO3F2 (KBBF), is still commercially unavailable because of the high toxicity of beryllium-containing and the extreme difficulty of crystal growth. Here, we report the crystal growth and characteristics of an beryllium-free polyphosphate, KLa(PO3...