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S6B). Collectively, these simulation results suggested the estimation of risk score can serve as an effective method for HCC detection at low sequencing depths. Attention map of DeepTrace identifies joint patterns of multiple CpG methylation with surrounding DNA sequence...
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maintenance cost refers to the repair of the whole solar evaporation device, whose lifespan is estimated as 10 years50,51. The maintenance costs were estimated as 3% of the capital costs per year and comprised 30% of the capital costs (estimation details are included in the supplementary Note...
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Nucleoplasmatic bridges are formed as a result of erroneous DNA repair and telomere fusion of two chromo- somes13. This process is triggered by critical telomere shortening and uncapping. However, to our knowledge, there is no indication that NPBs formation can lead to telomere elongation. Some ...
methylation and current well-established methylation-deconvolution methods to obtain the absolute contribution value from different cell types [69]. However, the inference accuracy of the methylation level in this approach is still not high enough for a robust and sensitive estimation of tissues-of-...
Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1. The Journal of biological chemistry 2002 Jun 21;277(25):23028-36 Kickhoefer VA, Siva AC, Kedersha NL, Inman EM, Ruland C, Streuli M, Rome LH The 193-...