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Retroviral integration, the process of covalently inserting viral DNA into the host genome, is a point of no return in the replication cycle. Yet, strand transfer is intrinsically iso-energetic and it is not clear how efficient integration can be achieve
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pool is quick and easy, with each air chamber able to be inflated in just 1 minute using an electric pump (not included). The pool features two water valves that double the drainage speed for convenient and efficient water removal. Safety ...
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(v1.8) was used to search coding structures based on transcriptome data and homologous proteins47. For the transcriptome-based annotation, pooled RNA-seq reads from the liver, brain, and stomach were mapped onto theC. nasusgenome by using Hisat2 (v 2.1.0)48with the following parameters:--...
[ 52 , 53 ]. the independence of the edges conditioned on vertex-weights even makes path-counting methods easier, in fact, we expect that the same proof that we provide here could be applied for these models as well. attack vulnerability the removal of all vertices above a certain degree ...
Chromatin compaction represents a major constraint limiting the timely access of DNA repair factors, which is crucial for efficient recognition and removal of DNA lesions18. Previously, we reported that BRCA1, a TF and chromatin remodeler, mediates responses of GBM cells to supra-physiological ...
However, once this pool of candidates is generated, state-of-the-art workflows rely on labor-intensive procedures (e.g., plasmid-based cloning, transfection, cell-based protein expression, protein purification, binding assess- ment through enzyme-linked immunosorbent assays (ELISAs), etc.) to ...