The single-arm, multicenter phase 2 trial evaluated the efficacy, safety, and tolerability of a new anticancer treatment in patients with locally advanced or metastatic anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer. The co-primary outcomes of the trial were objective tumor re...
Considerations During Preparation for Genomics Studies Involving Participants Typically Underrepresented in Research View LargeDownload Table 2. Framework Values and Success Metrics View LargeDownload Table 3. A Framework for Engagement of Diverse Participants in Genetics and Genomics Research View LargeDownload...
Delayed drug safety insights can impact patients, pharmaceutical companies, and the whole society. Post-market drug safety surveillance plays a critical role in providing drug safety insights, where real world evidence such as spontaneous reporting systems (SRS) and a series of disproportional analysis...
Involving patients in the development of the AI means that potentially harmful restrictions in treatment options can be addressed before the AI is deployed and that the AI's algorithm contains suitable individualisation options. Furthermore, patients' advocacy groups are often best placed to raise ...
Since 2015, Greece has hosted most refugees arriving in Europe. In the refugee camps, humanitarian organizations have reported unsafe and bad health condit
many studies have documented the changes in the fibroblastic component of carcinomas as they progress from hyperplasia, through adenoma or in situ lesion, to frank carcinoma in patients28. These studies using human tissue observe progressive changes in the fibroblastic stroma. In many cases, the ...
Figure 3. The framework for drivers of EMR uptake by health professionals. 3.1. Perceived Benefits Definition 1. “The degree of benefit healthcare professionals believe they gain from using EMRs, including improvements in patient safety, quality of care, documentation, decision-making, communication...
In one cluster randomized controlled trial, no significant improvement was observed in treatment outcome of TB patients as a result of an 18-h long participatory training program for clinic staff [27]. After the success of flight simulations, use of virtual reality was first proposed by Satava ...
Another important element is the minimization of unwarranted variations in healthcare services, variations that are associated with high costs and problems of patient safety [3]. In this context, finding effective ways to involve patients in shared decision making (SDM) is critical. SDM is defined...
For this project, in line with the MRC guidance for developing and evaluating complex interventions, stakeholders were considered to be individuals or groups whose personal or professional interests are affected by the framework, with patients and members of the public being considered key stakeholders ...