Define frameshift mutation. frameshift mutation synonyms, frameshift mutation pronunciation, frameshift mutation translation, English dictionary definition of frameshift mutation. n. A mutation in a DNA chain that occurs when the number of nucleotides in
Biology definition: Aframeshift mutationis a type ofgene mutationin which the addition or deletion of one or morenucleotidescauses a shift in thereading frameof thecodonsin themRNA, which may lead to the alteration in theamino acidsequence at proteintranslation.Variant:frame shift mutation.Synonyms...
Frameshift mutation can also be induced as a form of molecular therapy to cure and prevent different hereditary and genetic diseases. Frameshift mutation can also be used as a means to target cancer cells and their proteins to prevent such diseases. Frameshift mutation, when induced under controlled...
which is crucial for the prediction of the frame of the resulting frameshift peptides. As the translation of nucleotide into amino acid sequences is based on three base codons, every mutation in a homopolymer region can either result in a simple deletion or insertion of amino acids...
Definition of Frameshift Mutations A frameshift mutation occurs when there any insertion or deletion of more than one base pairs in the DNA and thus affects the nucleotide sequence and thus changes the amino acids too. Insertion Mutation: This type of mutation occurs when there is an insertion or...