Individual variability exists in parkinsonian motor symptoms despite a similar degree of nigrostriatal dopamine depletion in Parkinson's disease (PD), called motor reserve. We enrolled 397 patients newly diagnosed with PD who underwent dual-phaseF-FP-CIT PET upon initial assessment. Individual motor ...
【Keywords】 Parkinsondisease;Diagnosis;Tomography,emission2computed;FP2β2CIT 帕金森病(PD)的PET显像方法主要有应用 18 F2 左旋多巴(L2dopa)反映基底节L2dopa的代谢状态或 利用 11 C或 18 F标记特异性配体,显像基底节多巴胺 转运蛋白(DAT) [124]
F-Fp-CITPETcanevaluatetheParkinson'sdiseaseatthemolecularleve1.DATPETiSanimp ortanteliniealmolecular imagingtoo1. [Keywords]Positronemissiontomography;Parkinsoffsdisease;F-FP-CIT 多巴胺转运蛋白显像剂墙F—FP—CIT脑PET显像 评价脑内多巴胺能系统功能 ...
PET is an important clinicalmolecular imaging tool.[ Key words] Positron emission tomography ;Parkinson' s disease;18F-FP-CIT多巴胺转运蛋白显像剂 18 F-FP-CIT 脑 PET显像评价脑内多巴胺能系统功能管一晖 1 ,左传涛 1 ,张政伟 1 ,赵军 1 ,王坚 2 ,蒋雨平 2 ,陈正平 3 ,项景德 3 ,林祥通 1(1....
To investigate the usefulness of 18F-FP-CIT PET for assessing the severity of Parkinson’s disease (PD) at various clinical stages, 41 patients with PD were divided into early (Hoehn&Yahr I-II, n = 23) and advanced (Hoehn&Yahr III-IV, n = 18) subgroups. 18F-FP-CIT PET was performe...
$^{18}{rm F}$ -FP-CIT PET image was useful for diagnosis of Parkinson's disease (PD). Although spatial normalization step is necessary in SPM analysis, it was difficult to apply the spatial normalization on $^{18}{rm F}$-FP-CIT PET due to the lack of reference for spatial ...
99Tcm-TRODAT-1SPECT在早期PD诊断中类似于18F-FP-CIT,但无法早期发现病侧后壳核DAT值下降,DAT损害区反映偏侧PD的吻合率为81%。结论:18F-FP-CITPET纹状体DAT显像对早期PD诊断最佳。99Tcm-TRODAT-1纹状体DAT显像可用于早期PD诊断,适合国内目前应用。 展开 ...
[18F]FDG PET, [18F]FP-CIT PET and MR Morphometry in Lewy Body Dementia: Comparison with Alzheimer Disease (P6.081) BACKGROUND: Dementia in Parkinson's disease(PD) is characterized by executive dysfunction and impaired visuospatial construction ability, distinct from Alzheimer's disease(AD). ...
摘要:目的用简单等高线体积感兴趣区(VOI)法分析18FFP—CITPET图像中整个脑纹状体,旨在探究此方法鉴别特发性帕金森病(IPD)患者和正常人的价值,以及功能容量参数与IPD患者运动神经症状的关联。方法43例IPD患者和23名年龄匹配的健康者行18FFP—CITPET检查。应用专门的工作站,以梯度划分的方法自动勾画纹状体的VOI。比较IPD...
帕金森病患者临床量表UPDRS与^18F-FP-CIT PET-DAT功能显像相关性的研究,帕金森病患者临床量表UPDRS与^18F-FP-CIT PET-DA..