FOXO1-ada过表达的抗HER2 CAR-T细胞分化程度较低,CD62L+ 、CD27+、CD45RA+表型细胞的数量增加,同时耗竭标记物LAG3和TIM3的表达减少。 后续研究者构建了过表达FOXO1-ada的靶向Lewis Y的CAR-T细胞(重组人源细胞),发现其产生IFNγ和TNF的能力显著减弱,表明组成型活性FOXO1的表达限制了靶向Lewis Y的CAR-T细胞获得...
待分类 > FoxO1调节NF-kb、IL-1 下载文档 收藏 打印 转格式 86阅读文档大小:376.37K10页精品文档上传于2014-06-19格式:PDF 计算机知识windows系统:开始--运行--命令大全0421050529第一期 热度: 女孩要富养--杨澜269 热度: Cocos2d-x:Cocos2d-x事件处理与碰撞检测 ...
【2017年整理】NF-kb信号通路 热度: 金银花颗粒剂对调节兔耳痤疮NF-kB信号通路的实验研究 热度: PTEN-MediatedAkt/b-Catenin/Foxo1Signaling RegulatesInnateImmuneResponsesinMouse LiverIschemia/ReperfusionInjury NaokoKamo,BiboKe,RonaldW.Busuttil,andJerzyW.Kupiec-Weglinski ...
What is the TransAM NF-kB Flexi kit? Not all NF-kB sites are the same and our Flexi kits allow users to design and bind their own custom DNA oligonucleotides to the plate. This allows for the study of NF-kB dimers which bind to specific endogenous DNA sequences. ...
and respectively decreased and increased FOXO1 expression whereas increased and decreased NFE2L2 and NFKB1 expression in NHBECs and DHBECs, in association with respectively decreased and increased expression the SARS-CoV-2 entry genes ACE2 and TMPRSS2 and the tight junction protein genes TJP1 and...
NFKB1A nuclear factor kappa b subunit 1, SMURF1 smad specific e3 ubiquitin protein ligase 1, WWP2 WW domain containing E3 ubiquitin protein ligase 2, ATG2 autophagy related 2, SMURF2 smad specific e3 ubiquitin protein ligase 2, TGFB1 transforming growth factor β 1, PANBP9, MAPK8 mitogen...
s-3622R 细胞核因子|k基因结合核因子p52|p100抗体 NFkB p100|p52s-3324R 磷酸化血小板源性生长因子受体-B抗体 Phospho-PDGF Receptor beta (Tyr751)s-3626R 蛋白激酶C亚型G抗体 PKC gammas-3331R 磷酸化果糖-2,6-二磷酸酶3|磷酸果糖激酶2抗体 Phospho-PFKFB3|PFK2 (Ser467)s-3489R 磷酸化微管相关蛋白...
炎症因子、免疫 效应细胞 ( 如巨噬细胞浸润胰岛 细胞 ) 等通过 nf-b 信号通路都与 foxo1 磷酸化状态存在相关的2foxo1与2型糖尿病t2dm 的主要病理生理改变为靶组织 ( 主要为肝脏、肌肉 ) 的胰岛素抵抗伴胰岛素分泌不足。t2dm 患者体内产生胰岛素的能力并非完全丧失,有的患者体内胰岛素甚至产生过多,但胰岛素的作用...
人NFKB激活蛋白(NKAP)elisa检测试剂盒使用广泛 ¥ 1050.00 人EGF样域蛋白6(EGFL6)elisa检测试剂盒种属多样定量分析 ¥ 1050.00 商品描述 价格说明 联系我们 咨询底价 品牌: 联博科生物 产品名称: 大鼠叉头框蛋白O1(FOXO1)elisa检测试剂盒 产品规格: 96T 有效成分含量: 100 检测方法: 间接法,夹心法...
the accessibility in regions containing motifs associated with AP-1 and NF-κB subunit binding, in line with previous observations indicating that FOXO1 promotes a resting T cell state through repression of AP-1 activity41(Extended Data Fig.12a). Indeed, FOXO1 overexpression resulted in reduced ...