encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been ...
[3]Auricchio L,Adriani M,Frank J,et al. Nail dystrophy associated with a heterozygous mutation of the nude/SCID human FOXN1 (WHN) gene[J]. Arch Dermatol,2005,141:647-648. [4]Du Q,Huynh LK,Coskun F,et al. FOXN1 com...
transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, ...
(2002). Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice. Nat. Immunol. 3, 1102-1108.Wnt glyco-proteins regulate the expression of Foxn 1,the gene defectivein nude mice. Balciunaite G,Keller M,Balciunaite E,et al. Nature Immunology . 2002Balciunaite, ...
encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been ...
These mice carry loxP sites flanking target exons of Foxn1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Foxn1 gene. *使用本品系发表的文献需注明: Foxn1-Flox mice (Cat. NO. TBD) were purchased from ...
Indeed, no direct targets of Foxn1 in its transcriptional regulation of gene expression have been identified in TECs, despite the importance of Foxn1 in TEC development. Like b5t, many molecules, including DLL4, CCL25 and PD-L1, expressed in TECs have markedly reduced expression in Foxn1-...
裸鼠的胸腺芽基 regulatetheexpressionofFoxN1,the genedefectivein nude mice 不表达 CCL25和 CXCL12趋化因子,因此造血干细胞不能有 [J].NatImmunol,2002,3(11):1102—1108. 效地迁移至Foxnl缺失胸腺。Notch信号对于T细胞分化定 [9]OsadaM,JradineL,MisirR,eta1.DKK1mediatedinhibitionof Wntsignalinginpostnatal...
Association between mouse nude gene expression and the initiation of epithelial terminal differentiation. Dev Biol. 1999;208(2):362–74. Article CAS PubMed Google Scholar Gawronska-Kozak B, Grabowska A, Kur-Piotrowska A, Kopcewicz M. Foxn1 Transcription Factor Regulates Wound Healing of Skin ...
transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, ...