The Invention relates to a New formulation of Medicine that contains an antagonist of LTB of formula I, wherein a, R1, R2, R3,And R4 have the meaning indicated in claim 1, and their use as medicine.MOLL SIGLINDEBOCK THOMASWEBER KARLBECKER ROBERTSAUER ACHIMROSCHER RENEROTH ULRICH...
Determination of the Clinical Activity (Rachmilewitz) Index produces a score for a patient ranging from 0 to 29 points (higher scores meaning more severe disease). Clinical remission may be considered as a Clinical Activity (Rachmilewitz) Index score ≤4 points. Response as determined by the ...
Monitoring parameters and making changes can occur in a continuous process without the need to stop running. This allows quick reactions on demand, less waste, and more consistent quality. Less storage is needed as well. Handling errors are reduced, meaning there is less material "at risk." ...
Unless defined otherwise, all technical and scientific terms used herein have the meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In the specification, the following terms are defined: “PK” refers to an abbreviation of pharmacokinetic; “Ln”...
by the governments to protectpublic health. The main aim is controlling the safety and efficacy of products in areas includingpharmaceuticals, veterinary medicines, medical devices, pesticides, agrochemicals and cosmetics. Regulatory affairs also have a very specific meaning within the healthcare ...
meaning that it shoots out long growth tips which lean on the stems and branches of other plants, as well as boulders, trellises, fences, and walls; this can lead to the plant appearing untidy. The leaves are up to 15 cm (6 in) long. They are opposite, slightly serrated, green...
The mechanism of action of carbamazepine is stabilizes the inactivated state of sodium channels, meaning that fewer of these channels are available to subsequently open, making brain cells less excitable carbamazepine has also been shown to potentiate GABA receptors made up of α1, β2 and γ2 ...
An important parameter to consider when constructing a BMP product is that BMPs are pleiotropic proteins, meaning that they influence at least one or more molecular pathways beside their role in bone regeneration [26,27]. Therefore, their diffusion to nearby tissues can result in unwanted ectopic...
As used herein, the term “parenteral” is given its ordinary and customary meaning in the field of pharmaceutical drug routes of administration. According to the Food and Drug Administration's Center for Drug Evaluation and Research Data Standards Manual (CDER Data Element Number C-DRG-00301; Da...
It is also noted that in this disclosure, and particularly in the claims and/or paragraphs, terms such as “comprises”, “comprised”, “comprising” and the like can have the meaning attributed to it in US Patent law; e.g., they can mean “includes”, “included”, “including”, ...