Advantages with nasal systemic drug delivery: The nasal cavity is covered by a thin mucosa which is well vascularised.Therefore, a drug molecule can be transferred quickly across the single epithelial cell layer
Pardeshi CV, Rajput PV, Belgamwar VS, Tekade AR. Formulation, optimization and evaluation of spray-dried mucoadhesive microspheres as intranasal carriers for Valsartan, J Microencapsul., 2012: 29(2); 103-114.Pardeshi CV, Rajput PV, Belgamwar VS, Tekade AR. Formu- lation, optimization ...
Wareham, S. Clark, et al. Evaluation of the immunogenicity of mycobacterium bovis BCG delivered by aerosol to the lungs of macaques Clin Vaccin Immunol, 22 (2015), pp. 992-1003 View in ScopusGoogle Scholar 78 S.R. Rosenthal, J.T. McEnery, N. Raisys Aerogenic BCG vaccination against ...
At MedPharm, effective formulation starts with thoughtful planning. Our Evaluation & Planning Services provide the foundation for product success by integrating scientific rigor, strategic foresight, and regulatory insight. Before any batch is mixed, we ensure your therapeutic goals align with technical fe...
From feasibility trials with a few grams and providing samples with different specifications to scale-up production and evaluation of the process parameters. With dedicated clean room systems, we can micronize HAPI, hormons, controlled drugs and many more products, safely and according to GMP. Cont...
Effect of 3 months' nasal steroid therapy on nasal T cells and Langerhans cells in patients suffering from allergic rhinitis corticosteroid spray, fluticasone propionate aqueous nasal spray (FPANS), on Langerhans cells (CD1a + cells), HLA-DR + cells, and T cells in nasal ... AF Holm,WJ ...
(Evaluation) The formulations obtained in Examples 1 to 6, Comparative Examples 1 to 3 and Reference Examples 1 to 2 were evaluated for hairless rat skin permeability and rabbit skin primary irritation by the following tests. Hairless Rat Skin Permeability Test; ...
Evaluation of the efficacy, safety and pharmacokinetic profile of oral recombinant human parathyroid hormone [rhPTH(1-31)NH(2)] in postmenopausal women with osteoporosis Bone, 53 (1) (2013), pp. 160-166 View PDFView articleView in ScopusGoogle Scholar Homayoni et al., 2014 H. Homayoni, J...
Hosoya K., et al., Biol Pharm Bull Feb. 1994; 17 (2) : 316-22, “Evaluation of Enhancers to Increase Nasal Absorption Using Ussing Chamber Technique”, abstract. Tengamnuay P., et al., Pharm Res Apr. 1990; 7 (4) : 370-5, “Bile Salt-Fatty Acid Mixed Micelles as Nasal Absorptio...
With the increased involvement of staff and carers in the treatment of neonates, evaluation of the role of human factors could be particularly relevant during development. Studies should aim to mirror clinical practice where possible bearing in mind that the needs for each n...