Gelrite is an ion-activated polymer prepared by partial acetylation of gellan gum, an exogeneous polysaccharide present in Pseudomonas elodea. Its unique cation-dependent gelling property at 33°C has been exploited for the formulation of in situ gelling hydrogels for ophthalmic and oral drug delivery...
Formulation and Evaluation of Two Anti-inflammatory Herbal GelsAcacia nilotica Delanti-inflammatoryherbal formulationtopical gelQuercus infectoria OlivTwo herbal gels expected to produce a topical anti-inflammatory activity were formulated, characterized and evaluated both phytochemically and biologically. The ...
Eyedrops based on a thermoresponsive polymer were developed by mixing poly(acrylic acid-graft-N-isopropylacrylamide) (PAAc-graft-PNIPAAm) with PAAc-co-PNIPAAm gel and incorporating [3H]-epinephrine for in vitro evaluation of ophthalmic drug release. Polymeric eyedrops are clear solutions at room ...
INTERNATIONAL JOURNAL OF DRUG FORMULATION AND RESEARCH FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF ATENOLOL BY DIRECT COMPRESSION METHOD Atenolol is a 尾 1 selective antagonist without membrane stabilizing or intrinsic sympathomimetic activities. Administration of conventional tablets of ate... ...
Metformin is an antidiabetic drug which possesses antiproliferative activity in cancer cells when administered at high doses, due to its unfavorable pharmacokinetics. The aim of this work was to develop a pharmacological tool for the release of metformin
Injectable PAMAM dendrimer-PEG hydrogels for the treatment of genital infections: formulation and in vitro and in vivo evaluation. Local intravaginal drug therapy is preferred for treatment of ascending genital infections during pregnancy. In the present study, an in situ forming biode... RS Navath...
Release behavior of ketoprofen relied on the preparative methods of matrices, ratios of CGG/AA and pH environments. The release mechanism was studied by ... Y Huang,H Yu,C Xiao - 《Carbohydrate Polymers》 被引量: 218发表: 2007年 Evaluation of novel soya-lecithin formulations for dermal use ...
PLGA nanoparticle formulations of risperidone: preparation and neuropharmacological evaluation. Nanomedicine 5, 323–333 (2009). CAS PubMed Google Scholar Dunbar, J. L. et al. Single- and multiple-dose pharmacokinetics of long-acting injectable naltrexone. Alcohol Clin. Exp. Res. 30, 480–490 ...
Nanohydrogels composed of hydrophobized HA and AmB were Conclusions In the present study, we investigated a nanohydrogel ocular formulation by loading AmB into hydrophobized HA. AHA/AmB is water-soluble. As this formulation interacts with mucin in vitro, improved corneal retention can be expected...
and PEGylation, have fulfilled some but not all of their promises, while hydrogels and lipid-based formulations could well be developed into generic delivery systems. Strategies to curb the aggregation and misfolding of proteins during storage are likely to benefit from the recent surge of ...