To derive a useful formula for calculating recommended glargine doses, we analyzed data from the Add-on LantusH to Oral Hypoglycemic Agents (ALOHA) study, a 24-week observation of Japanese type 2 diabetes patients. Methodology/Principal Findings:The patients who initiated insulin glargine in basal...
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from clinical dosage using the following formula: MQLF dosage = 174 g × 6.17/60 kg. The clinical drug dosage of QLF was 174 g/person/day, and the average body weight of normal adults was 60 kg, resulting in an equivalent dose ratio of 6.17 between rats and humans. Except for the ...
The energy intake, expenditure, and deposi- NCHS, National Center for Health Statistics tion of 40 breast-fed and formula-fed infants were investi- EE02, postprandial energy expenditure at 0 to 2 h gated at 1 and 4 mo of age to explore possible differences EE23, postprandial energy ...
It could reduce the infection of the virus in a dose- and time-dependent manner, as confirmed by observing the cell cytopathic effect and calculating the cell viability (p < 0.05). SWHD demonstrated better antiviral activity than oseltamivir in the evaluation of antiviral prophylaxis on influenza...
et al. Identification of the effective constituents for anti-inflammatory activity of Ju-Zhi-Jiang-Tang, an ancient traditional Chinese medicine formula. J. Chromatogr. A 1348, 105–124 (2014). Article CAS PubMed Google Scholar Jiang, Z. et al. Dose-dependent targeted knockout methodology ...
[23] proposed the GEPSI method to identify the target proteins of CM by calculating the similarities of gene expression. These reports are promising for the application of DNA microarray technology in the research of CM. However, other high-throughput technologies such as exome sequencing, MeDIP...
INSULIN derivativesBODY weightThere is no standard formula for estimating the starting daily dose (SDD) of basal-bolus insulin therapy (BBT). We aimed to develop a formula for estimating SDD and evaluate its efficacy and safety in patients with type 2 diabetes hospitalized for BBT. In the ...
Considering that OB is one of the most desirable attributes of new drugs which represents the ratio of the orally-administered dose that reaches the circulation system with their activity unchanged, we introduced a robust in house system, OBioavail1.155, to predict the OB value for drugs, which...
the calculating formula was the same as that in GO analysis. For Gene Set Enrichment Analysis (GSEA) analysis, 3 major steps included calculation of an enrichment score (ES), estimation of significance level of ES, and adjustment for multiple hypothesis testing by FDR calculating based on GSEA ...