Novel forms of prostate cancer chemoresistance to successful androgen deprivation therapy demand new approaches: Rationale for targeting BET proteinsandrogen deprivation therapybromodomain and extra‐terminal proteinscastration‐resistant prostate cancerIn patients with prostate cancer, the duration of remission ...
Diagnostic value of molecular forms of prostate-specific antigen for female breast cancer Objectives: To examine the diagnostic value of prostate-specific antigen (PSA) subfractions in the serum of female breast cancer patients. Design and Metho... MEP Diamandis - 《Clinical Biochemistry》 被引量:...
The new study expanded the analysis to metastatic cancer, when the disease spreads from the prostate. Metastatic prostate cancer is much more lethal than its local version. It's also more difficult to study, because small tumors can be in many different parts of the body and are harder to b...
This suggests that routine analysis of molecular forms of PSA could improve the utility of the change in total PSA associated with finasteride for the early diagnosis of prostate cancer. It also suggests that any subsequent change in both ratios, particularly an increase in c/tPSA or a decrease...
In this article, you will learn of the three most importantformsof selenium—and how each has the power to halt cancer development at its earliest stages. Exciting data on their ability to combat cancers of thecolonandprostateare detailed. You will discover the12mechanisms of action by which ...
We compared 90 consecutive men who had 2 sets of 6 negative systematic biopsies with 70 who had at least 5 mm. of prostate cancer in systematic biopsies during the same period at our institution. Total prostate and transition zone volumes were determined by transrectal ultrasound. The Bayer, ...
Brown JE, Cook RJ, Major P, Lipton A, Saad F, Smith M, Lee KA, Zheng M, Hei YJ, Coleman RE (2005) Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors. J Natl Cancer Inst 97:59–69 Article CAS PubMed Google Scholar...
The diagnostic specificity of prostate specific antigen (PSA) is limited. We aimed to characterize eight anti-PSA monoclonal antibodies (mAbs) to assess the prostate cancer (PCa) diagnostic utility of different PSA molecular forms, total (t) and free (f)
A urine test for prostate cancer itself would be a huge improvement on the current status quo, but one patients can use in the comfort of their own home would be even better. Rather than having to visit the clinic regularly for checkups and biopsies, at-risk patients could simply monitor ...
Methods and compositions for the identification and assessment of prostate cancer therapies and the diagnosis of prostate cancer The invention concerns two classes of differentially regulated genes: 1) genes that are more highly expressed in prostate cancer cells treated with testosterone than in ...