Alzheimer DiseaseParkinson DiseasePersonalized MedicineWe can expect that a better understanding of the pathogenesis of systemic lupus erythematosus (SLE) will eventually lead to improved treatments for this devastating disorder ('translational medicine'). And if lupus is not a single disease entity, ...
ContextThe reason that only some patients with lupus erythematosus (LE) develop autoantibodies to SS-A/Ro and SS-B/La antigens and photosensitivity is
In the syndromes of autoantibodies to the insulin receptor, the various forms of lupus glomerulonephritis are seen. Even in patients with type 2 diabetes, the renal pathology may not be diabetic nephropathy. Therefore, in patients with syndromic forms of insulin resistance and type 2 diabetes, ...
The pathogenesis of lupus nephritis (LN) has not been fully understood. The renin-angiotensin system (RAS) is implicated in various immunological and non-immunological phenomena, and the polymorphism of the RAS genes has been associated with cardiovascular and renal disease onset and outcome. Therefor...
133 In a mouse model of lupus, bortezomib depleted both short- and long-lived plasma cells, resulting in a reduction of anti-double-stranded DNA antibody production.170 Vogelbacher et al. recently established that bortezomib alone or in combination with sirolimus can also prevent alloantibody ...
The role of the anaphylatoxins in health and disease September 2009 Andreas Klos,…, Jörg Köhl View more articles Recommended articles Interactions among glomerulus infiltrating macrophages and intrinsic cells via cytokines in chronic lupus glomerulonephritis Journal of Autoimmunity, Volume 106, 2020,...
PURPOSE: In patients with metastatic disease to the spine, patient selection for surgery and the extent of surgery to perform thereafter remains controvers... V Pointillart,JM Vital,R Salmi,... - 《J Cancer Res Clin Oncol》 被引量: 108发表: 2011年 Prognostic factors of lupus myelopathy Mye...
Lupus nephritis: Clinical course as related to morphologic forms and their transitions An intensive study of the course of lupus nephritis has been undertaken in 88 patients in whom strict morphologic criteria were utilized in classification. All were treated with steroid, and 17 received cytotoxic ...
Ko JY, Kim YS, Lee CW. Multifocal lesions of morphoea in a patient with systemic lupus erythematosus. Clin Exp Dermatol. 2009;34(8):e676–9. ArticlePubMedCASGoogle Scholar Firoz EF, Kamino H, Lehman TJ, Orlow SJ. Morphea, diabetes mellitus type I, and celiac disease: case report and...
Spontaneous anti-Id antibodies were found in all clinical forms of disease. The majority of patients (88%, n = 8) with the acute form of PCM had high titers of Ab2. However, among patients with the multifocal chronic form of the disease, only 29% (n = 14) had high titers of Ab2;...