Background Horizontal gene transfer (HGT) has greatly impacted the genealogical history of many lineages, particularly for prokaryotes, with genes frequently moving in and out of a line of descent. Many genes that were acquired by a lineage in the past likely originated from ancestral relatives ...
Therefore, a "vertical" inheritance from a hypothetical eukaryotic trans-sialidase gene expressed in insect forms of trypanosomes is more likely to have occurred than the horizontal gene transfer from bacteria, and thus explains the presence of this enzyme in the mammalian infective forms of ...
C. CRISPR-Cas-mediated phage resistance enhances horizontal gene transfer by transduction. mBio 9, e02406-17 (2018). PubMed PubMed Central Google Scholar Frampton, R. A. et al. Identification of bacteriophages for biocontrol of the kiwifruit canker phytopathogen Pseudomonas syringae pv. ...
The type VI secretion system (T6SS) ofPseudomonas aeruginosainjects effector proteins into neighbouring competitors and host cells, providing a fitness advantage that allows this opportunistic nosocomial pathogen to persist and prevail during the onset of infections. However, despite the high clinical rel...
The deletion mutants lack either the amino-terminal 33 amino acids of the I domain (residues 628-660) or the COOH-terminal 23 amino acids of the I domain (amino acids 661-683), as indicated by the horizontal bars. Samples from cells transfected with wild-type or mutated meprin α subunit...
The right view represents the left view rotated by 90° around the horizontal axis. (B) A stereoview of the final set of 19 structures superimposed over ordered residues (defined in Table 2). Coloring is as in (A). Mj0056 shows a six-stranded β-barrel fold (Figure 5) with the ...
Relative Intensity (in counts) is shown on the vertical axis and the degrees (2θ) is shown on the horizontal axis. FIG. 4 is a characteristic X-Ray Powder Diffraction (XRPD) pattern obtained from Form A of ponatinib hydrochloride. Relative Intensity (in counts) is shown on the vertical ...
horizontal gene transferrisk assessmentThe enzyme CP4 5-enolpyruvyl shikimate-3-phosphate synthase (EPSPS; EC 2.5.1.19) from Agrobacterium tumefaciens CP4, encoded by the aro A gene, has been used for the construction of genetically modified crops resistant to total herbicide glyphosate. During the...
Since the extension of rhizobia genome diversity results from the horizontal sym gene transfer occurring with low frequencies, we suggest that this extension is due to the frequency-dependent selection anchoring the rare genotypes in bacterial populations. It is implemented during the rhizobia competition...
We were not able to detect the episomal form of this GI, probably due to a mutated attR site. However, we could demonstrate that integrative GIs are present in Francisella and that they may allow horizontal gene transfer between different Francisella species....