Of note, both Gp5−/− and Gp5dThr platelet-rich plasma (PRP) showed unaltered clot retraction (Extended Data Fig. 1j). We next tested the hypothesis that membrane-bound GPV might act as a regulator of thrombin-mediated PAR activation25, supported by the high-affinity binding of thrombin...
Beside nosocomial infections, clot formation affects cardiovascular medical devices and central venous catheters implants. In order to reduce and prevent such infection, we develop a plasma-assisted process for the deposition of nanostructured functional coatings on flat substrates...
Papapostolou S, Andrianopoulos N, Duffy SJ, Brennan AL, Ajani AE, Clark DJ et al (2018) Long-term clinical outcomes of transient and persistent no-reflow following percutaneous coronary intervention (PCI): a multicentre Australian registry. EuroIntervention 14:185–193 Article PubMed Google Scholar...
4. Neutrophils, the most abundant immune cell type in circulation, contribute to the first line of defence against a large number of pathogens and are critical in this fine balance as their antimicrobial
Bone.(a) This cross-sectional view of compact bone shows the basic structural unit, the osteon. (b) In this micrograph of the osteon, you can clearly see the concentric lamellae and central canals. LM × 40. (Micrograph provided by the Regents of University of Michigan Medical School ©...
c. They may die a sudden death, called an infarct. d. They may change from one type to anoth Discuss the consequences of the failure of a formed clot to dissolve. What is a disadvantage of epithelial tissue being avascular? What condition ...
The role of leukocytes in deep vein thrombosis (DVT) resolution is incompletely understood. We determined how depletion of lysozyme positive (LysM+) cells and a switched-off type 1 immune response influences thrombus resolution. DVT was induced in 12-wee
The present work demonstrated a novel strategy that rapid type H vessel angiogenesis and osteogenesis mediated by the microenvironment might be favorable for enhanced osseointegration of polymer implants. 2. Method Primary HUVECs were obtained from umbilical cords taken after delivery of healthy term ...
The first stage of the healing process is hemostasis, consisting of coagulation and platelet activation at the site of injury. These events serve to rapidly stem blood loss by the formation of a fibrin clot, and occur shortly after the injury (typically within minutes). The coagulation process ...
Bile duct tumor thrombosis (BDTT) is a severe complication that most likely occurred in advanced hepatocellular carcinoma (HCC) patients, which can cause a rapid decline in quality of life (i.e., obstructive jaundice) and associate with worse clinical outcome1,2,3. However, HCC patients with...